Reactome | UBE2N:UBE2V1 [cytosol]

Schema > Complex > Entries

UBE2N:UBE2V1 [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-RNO-9640491] Ub:UBE2N:UBE2V1 [cytosol] - Rattus norvegicus [Complex:R-RNO-8948058] K63polyUb-hp-IRAK1:p-Pellino-1,2,(3):UBE2N:UBE2V1 [cytosol] - Rattus norvegicus [Complex:R-RNO-450144] hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] - Rattus norvegicus [Complex:R-RNO-450144] hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] - Rattus norvegicus [Complex:R-RNO-450144] hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] - Rattus norvegicus
consumedByEvent	[BlackBoxEvent:R-RNO-202534] Ubiquitination of NEMO by TRAF6 - Rattus norvegicus [BlackBoxEvent:R-RNO-2730904] Auto-ubiquitination of TRAF6 - Rattus norvegicus [BlackBoxEvent:R-RNO-9758604] Ubiquitination of IKBKG by TRAF6 - Rattus norvegicus [Reaction:R-RNO-975122] Pellino ubiquitinates hp-IRAK1 upon TLR7/8 or 9 activation - Rattus norvegicus [BlackBoxEvent:R-RNO-5607757] K63polyUb-TRAF6 ubiquitinates TAK1 - Rattus norvegicus [Reaction:R-RNO-202453] Auto-ubiquitination of TRAF6 - Rattus norvegicus [Reaction:R-RNO-202453] Auto-ubiquitination of TRAF6 - Rattus norvegicus [Reaction:R-RNO-202453] Auto-ubiquitination of TRAF6 - Rattus norvegicus [BlackBoxEvent:R-RNO-5607756] TRAF6 oligomer autoubiquitinates - Rattus norvegicus [Reaction:R-RNO-937050] Pellino ubiquitinates hp-IRAK1 - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10117489
displayName	UBE2N:UBE2V1 [cytosol]
hasComponent	[EntityWithAccessionedSequence:R-RNO-206072] Ube2n [cytosol] [EntityWithAccessionedSequence:R-RNO-205753] UBE2V1 [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-202463] UBE2N:UBE2V1 [cytosol] - Homo sapiens
maxDepth	2
memberOf	[DefinedSet:R-RNO-9834952] UBE2D2,UBE2D3,UBE2N:UBE2V1,UBE2L3 [cytosol] - Rattus norvegicus
name	UBE2N:UBE2V1
producedByEvent	[BlackBoxEvent:R-RNO-202534] Ubiquitination of NEMO by TRAF6 - Rattus norvegicus [BlackBoxEvent:R-RNO-2730904] Auto-ubiquitination of TRAF6 - Rattus norvegicus [BlackBoxEvent:R-RNO-9758604] Ubiquitination of IKBKG by TRAF6 - Rattus norvegicus [Reaction:R-RNO-975122] Pellino ubiquitinates hp-IRAK1 upon TLR7/8 or 9 activation - Rattus norvegicus [BlackBoxEvent:R-RNO-5607757] K63polyUb-TRAF6 ubiquitinates TAK1 - Rattus norvegicus [Reaction:R-RNO-202453] Auto-ubiquitination of TRAF6 - Rattus norvegicus [Reaction:R-RNO-202453] Auto-ubiquitination of TRAF6 - Rattus norvegicus [Reaction:R-RNO-202453] Auto-ubiquitination of TRAF6 - Rattus norvegicus [BlackBoxEvent:R-RNO-5607756] TRAF6 oligomer autoubiquitinates - Rattus norvegicus [Reaction:R-RNO-937050] Pellino ubiquitinates hp-IRAK1 - Rattus norvegicus [BlackBoxEvent:R-RNO-8948066] K63polyUb-IRAK1 dissociates - Rattus norvegicus [BlackBoxEvent:R-RNO-8948018] UBE2N:UBE2V1 dissociates from hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 - Rattus norvegicus [BlackBoxEvent:R-RNO-8948018] UBE2N:UBE2V1 dissociates from hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 - Rattus norvegicus [BlackBoxEvent:R-RNO-8948018] UBE2N:UBE2V1 dissociates from hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 - Rattus norvegicus
schemaClass	Complex
species	[Species:48895] Rattus norvegicus
stId	R-RNO-202463
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Referrals

(output)	[Reaction:R-RNO-975122] Pellino ubiquitinates hp-IRAK1 upon TLR7/8 or 9 activation [BlackBoxEvent:R-RNO-8948066] K63polyUb-IRAK1 dissociates [BlackBoxEvent:R-RNO-202534] Ubiquitination of NEMO by TRAF6 [BlackBoxEvent:R-RNO-5607757] K63polyUb-TRAF6 ubiquitinates TAK1 [BlackBoxEvent:R-RNO-5607756] TRAF6 oligomer autoubiquitinates [Reaction:R-RNO-202453] Auto-ubiquitination of TRAF6 [BlackBoxEvent:R-RNO-2730904] Auto-ubiquitination of TRAF6 [BlackBoxEvent:R-RNO-8948018] UBE2N:UBE2V1 dissociates from hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [BlackBoxEvent:R-RNO-9758604] Ubiquitination of IKBKG by TRAF6 [Reaction:R-RNO-937050] Pellino ubiquitinates hp-IRAK1
(input)	[Reaction:R-RNO-975122] Pellino ubiquitinates hp-IRAK1 upon TLR7/8 or 9 activation [BlackBoxEvent:R-RNO-202534] Ubiquitination of NEMO by TRAF6 [BlackBoxEvent:R-RNO-5607757] K63polyUb-TRAF6 ubiquitinates TAK1 [BlackBoxEvent:R-RNO-5607756] TRAF6 oligomer autoubiquitinates [Reaction:R-RNO-202453] Auto-ubiquitination of TRAF6 [BlackBoxEvent:R-RNO-2730904] Auto-ubiquitination of TRAF6 [BlackBoxEvent:R-RNO-9758604] Ubiquitination of IKBKG by TRAF6 [Reaction:R-RNO-937050] Pellino ubiquitinates hp-IRAK1
(hasComponent)	[Complex:R-RNO-8948058] K63polyUb-hp-IRAK1:p-Pellino-1,2,(3):UBE2N:UBE2V1 [cytosol] [Complex:R-RNO-1248657] TRAF6 E3/E2 ubiquitin ligase complex [cytosol] [Complex:R-RNO-450144] hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] [Complex:R-RNO-9640491] Ub:UBE2N:UBE2V1 [cytosol] [Complex:R-RNO-9641124] UBE2N:UBE2V1:PRKN [cytosol]
(hasMember)	[DefinedSet:R-RNO-9834952] UBE2D2,UBE2D3,UBE2N:UBE2V1,UBE2L3 [cytosol]
(inferredTo)	[Complex:R-HSA-202463] UBE2N:UBE2V1 [cytosol]

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