Reactome | phospho-Akt1s1 [cytosol]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-RNO-5672861] p-S183,S221,T246-AKT1S1:YWHAB [lysosomal membrane] - Rattus norvegicus
consumedByEvent	[Reaction:R-RNO-5672824] Phosphorylated AKT1S1 binds YWHAB - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10124389
displayName	phospho-Akt1s1 [cytosol]
endCoordinate	256
hasModifiedResidue	[ModifiedResidue:10124385] O-phospho-L-serine at 183 (in Homo sapiens) [ModifiedResidue:10124386] O-phospho-L-threonine at 246 (in Homo sapiens) [ModifiedResidue:10124387] O-phospho-L-serine at 221 (in Homo sapiens)
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-200163] p-S183,S221,T246-AKT1S1 [cytosol] - Homo sapiens
maxDepth	1
name	phospho-Akt1s1 p-S183,S221,T246-AKT1S1 A0A8I5ZRQ9
producedByEvent	[Reaction:R-RNO-200143] AKT phosphorylates AKT1S1 (PRAS40) - Rattus norvegicus [Reaction:R-RNO-5672828] mTORC1 phosphorylates AKT1S1 - Rattus norvegicus
referenceEntity	[ReferenceGeneProduct:uniprot:A0A8I5ZRQ9] UniProt:A0A8I5ZRQ9
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48895] Rattus norvegicus
stId	R-RNO-200163
startCoordinate	1

(input)	[Reaction:R-RNO-5672824] Phosphorylated AKT1S1 binds YWHAB
(hasComponent)	[Complex:R-RNO-5672861] p-S183,S221,T246-AKT1S1:YWHAB [lysosomal membrane]
(output)	[Reaction:R-RNO-5672828] mTORC1 phosphorylates AKT1S1 [Reaction:R-RNO-200143] AKT phosphorylates AKT1S1 (PRAS40)
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-200163] p-S183,S221,T246-AKT1S1 [cytosol]

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