Reactome | phospho-Rb1 [nucleoplasm]

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phospho-Rb1 [nucleoplasm] Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
consumedByEvent	[Reaction:R-RNO-113503] PP2A mediated localization of RB1 protein in chromatin - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10112692
displayName	phospho-Rb1 [nucleoplasm]
endCoordinate	928
hasModifiedResidue	[ModifiedResidue:10103761] O-phospho-L-serine at 795 (in Homo sapiens) [ModifiedResidue:10103740] O-phospho-L-serine at 230 (in Homo sapiens) [ModifiedResidue:10103743] O-phospho-L-serine at 249 (in Homo sapiens) [ModifiedResidue:10103746] O-phospho-L-threonine at 252 (in Homo sapiens) [ModifiedResidue:10103749] O-phospho-L-serine at 608 (in Homo sapiens) [ModifiedResidue:10103752] O-phospho-L-serine at 612 (in Homo sapiens) [ModifiedResidue:10103755] O-phospho-L-serine at 780 (in Homo sapiens) [ModifiedResidue:10103758] O-phospho-L-serine at 788 (in Homo sapiens) [ModifiedResidue:10103764] O-phospho-L-serine at 807 (in Homo sapiens) [ModifiedResidue:10103767] O-phospho-L-serine at 811 (in Homo sapiens) [ModifiedResidue:10103770] O-phospho-L-threonine at 356 (in Homo sapiens) [ModifiedResidue:10103773] O-phospho-L-threonine at 373 (in Homo sapiens) [ModifiedResidue:10103776] O-phospho-L-threonine at 821 (in Homo sapiens) [ModifiedResidue:10103779] O-phospho-L-threonine at 826 (in Homo sapiens)
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-188389] hyperphosphorylated RB1 [nucleoplasm] - Homo sapiens
maxDepth	1
memberOf	[DefinedSet:R-RNO-187920] p-FZR1,p-RB1 [nucleoplasm] - Rattus norvegicus
name	phospho-Rb1 hyperphosphorylated RB1 P33568
producedByEvent	[Reaction:R-RNO-188390] Cyclin E:CDK2-mediated phosphorylation of RB1 - Rattus norvegicus [Reaction:R-RNO-188390] Cyclin E:CDK2-mediated phosphorylation of RB1 - Rattus norvegicus [Reaction:R-RNO-188390] Cyclin E:CDK2-mediated phosphorylation of RB1 - Rattus norvegicus [Reaction:R-RNO-188390] Cyclin E:CDK2-mediated phosphorylation of RB1 - Rattus norvegicus [Reaction:R-RNO-188390] Cyclin E:CDK2-mediated phosphorylation of RB1 - Rattus norvegicus [Reaction:R-RNO-188390] Cyclin E:CDK2-mediated phosphorylation of RB1 - Rattus norvegicus [Reaction:R-RNO-188390] Cyclin E:CDK2-mediated phosphorylation of RB1 - Rattus norvegicus [Reaction:R-RNO-188390] Cyclin E:CDK2-mediated phosphorylation of RB1 - Rattus norvegicus [Reaction:R-RNO-188390] Cyclin E:CDK2-mediated phosphorylation of RB1 - Rattus norvegicus [Reaction:R-RNO-188390] Cyclin E:CDK2-mediated phosphorylation of RB1 - Rattus norvegicus [Reaction:R-RNO-188390] Cyclin E:CDK2-mediated phosphorylation of RB1 - Rattus norvegicus [Reaction:R-RNO-188390] Cyclin E:CDK2-mediated phosphorylation of RB1 - Rattus norvegicus [Reaction:R-RNO-188390] Cyclin E:CDK2-mediated phosphorylation of RB1 - Rattus norvegicus [Reaction:R-RNO-188390] Cyclin E:CDK2-mediated phosphorylation of RB1 - Rattus norvegicus
referenceEntity	[ReferenceGeneProduct:uniprot:P33568] UniProt:P33568
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48895] Rattus norvegicus
stId	R-RNO-188389
startCoordinate	2

Referrals

(hasMember)	[DefinedSet:R-RNO-187920] p-FZR1,p-RB1 [nucleoplasm]
(input)	[Reaction:R-RNO-113503] PP2A mediated localization of RB1 protein in chromatin
(output)	[Reaction:R-RNO-188390] Cyclin E:CDK2-mediated phosphorylation of RB1
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-188389] hyperphosphorylated RB1 [nucleoplasm]

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