Reactome | Synthesis of IPs in the nucleus

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Synthesis of IPs in the nucleus Show undefined attributes

created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10224327
displayName	Synthesis of IPs in the nucleus
eventOf	[Pathway:R-RNO-1483249] Inositol phosphate metabolism - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:258976] inositol phosphate metabolic process
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-RNO-1855233] I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by IPMK in the nucleus - Rattus norvegicus [Reaction:R-RNO-1855206] I(1,3,4,5)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus - Rattus norvegicus [Reaction:R-RNO-1855228] I(1,3,4,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus - Rattus norvegicus [Reaction:R-RNO-1855185] I(1,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by IPMK in the nucleus - Rattus norvegicus [Reaction:R-RNO-1855176] I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK (IP5-2K) in the nucleus - Rattus norvegicus [Reaction:R-RNO-1855181] I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/2 in the nucleus - Rattus norvegicus [Reaction:R-RNO-1855230] 5-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/2 in the nucleus - Rattus norvegicus [Reaction:R-RNO-1855207] IP6 is phosphorylated to 5-PP-IP5 by IP6K1/2 in the nucleus - Rattus norvegicus [Reaction:R-RNO-1855224] 5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/2 in the nucleus - Rattus norvegicus [Reaction:R-RNO-1855157] 1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/2 in the nucleus - Rattus norvegicus
inferredFrom	[Pathway:R-HSA-1855191] Synthesis of IPs in the nucleus - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Synthesis of IPs in the nucleus
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48895] Rattus norvegicus
stId	R-RNO-1855191
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-1483249] Inositol phosphate metabolism
(inferredTo)	[Pathway:R-HSA-1855191] Synthesis of IPs in the nucleus

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