Reactome | Association of Securin with Cdc20:APC/C complex

Schema > Reaction > Entries

Association of Securin with Cdc20:APC/C complex Show undefined attributes

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10119037
displayName	Association of Securin with Cdc20:APC/C complex
eventOf	[Pathway:R-RNO-174154] APC/C:Cdc20 mediated degradation of Securin - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-RNO-174144] Ubiquitination of Securin by phospho-APC/C:Cdc20 complex - Rattus norvegicus
inferredFrom	[Reaction:R-HSA-174121] Association of Securin with Cdc20:APC/C complex - Homo sapiens
input	[Complex:R-RNO-174081] CDC20:p-APC/C [cytosol] [EntityWithAccessionedSequence:R-RNO-174190] Pttg1 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Association of Securin with Cdc20:APC/C complex
output	[Complex:R-RNO-174212] CDC20:p-APC/C:PTTG1 [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-174121
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-174154] APC/C:Cdc20 mediated degradation of Securin [Pathway:R-RNO-2467813] Separation of Sister Chromatids
(precedingEvent)	[Reaction:R-RNO-174144] Ubiquitination of Securin by phospho-APC/C:Cdc20 complex
(inferredTo)	[Reaction:R-HSA-174121] Association of Securin with Cdc20:APC/C complex

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