Reactome | Nuclear Pore Complex (NPC) [nuclear envelope]

Schema > Complex > Entries

Nuclear Pore Complex (NPC) [nuclear envelope] Show undefined attributes

catalystActivities	[CatalystActivity:10168873] SUMO transferase activity of Nuclear Pore Complex (NPC) [nuclear envelope] [CatalystActivity:10117880] structural constituent of nuclear pore activity of Nuclear Pore Complex (NPC) [nuclear envelope] [CatalystActivity:10158550] narrow pore channel activity of Nuclear Pore Complex (NPC) [nuclear envelope]
compartment	[Compartment:13231] nuclear envelope
componentOf	[Complex:R-RNO-113815] NPC:NXF1,2:NXT1:EJC:CBC:mRNA [nucleoplasm] - Rattus norvegicus
consumedByEvent	[Reaction:R-RNO-2990882] CDK1 phosphorylates NUP98 - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10109212
displayName	Nuclear Pore Complex (NPC) [nuclear envelope]
hasComponent	8 × [EntityWithAccessionedSequence:R-RNO-157738] Aaas [nuclear envelope] 16 × [GenomeEncodedEntity:R-RNO-157750] Ghost homologue of SEH1L-2 [nuclear envelope] 32 × [EntityWithAccessionedSequence:R-RNO-6805183] Ndc1 [nuclear envelope] 32 × [Complex:R-RNO-377883] Nup107-160 complex [cytosol] 8 × [EntityWithAccessionedSequence:R-RNO-157695] NUP153 [nucleoplasm] 16 × [EntityWithAccessionedSequence:R-RNO-157752] Nup188 [nuclear envelope] 16 × [EntityWithAccessionedSequence:R-RNO-157722] Nup210 [nuclear envelope] 8 × [EntityWithAccessionedSequence:R-RNO-157691] Nup214 [cytosol] 16 × [EntityWithAccessionedSequence:R-RNO-157697] Nup42 [cytosol] 32 × [EntityWithAccessionedSequence:R-RNO-157740] Nup50 [nucleoplasm] 32 × [Complex:R-RNO-157712] Nup62 Complex [nuclear envelope] 32 × [EntityWithAccessionedSequence:R-RNO-157753] Nup88 [cytosol] 32 × [Complex:R-RNO-9634183] Nup93 complex [nuclear envelope] 8 × [EntityWithAccessionedSequence:R-RNO-2990912] Nup98 [nuclear envelope] 16 × [EntityWithAccessionedSequence:R-RNO-157747] Pom121 [nuclear envelope] 48 × [EntityWithAccessionedSequence:R-RNO-157718] Rae1 [nuclear envelope] 8 × [EntityWithAccessionedSequence:R-RNO-157703] Ranbp2 [cytosol] 16 × [EntityWithAccessionedSequence:R-RNO-157692] Tpr [nucleoplasm]
inDisease	false
inferredFrom	[Complex:R-HSA-157689] Nuclear Pore Complex (NPC) [nuclear envelope] - Homo sapiens
isRequired	[Requirement:10109439] Requirement by 'Nuclear Pore Complex (NPC) [nuclear envelope]'
maxDepth	3
name	Nuclear Pore Complex (NPC)
positivelyRegulates	[Requirement:10109439] Requirement by 'Nuclear Pore Complex (NPC) [nuclear envelope]'
producedByEvent	[Reaction:R-RNO-75098] mRNP complex dissociates from cytosolic face of NPC - Rattus norvegicus
schemaClass	Complex
species	[Species:48895] Rattus norvegicus
stId	R-RNO-157689
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Referrals

(physicalEntity)	[CatalystActivity:10168873] SUMO transferase activity of Nuclear Pore Complex (NPC) [nuclear envelope] [CatalystActivity:10117880] structural constituent of nuclear pore activity of Nuclear Pore Complex (NPC) [nuclear envelope] [CatalystActivity:10158550] narrow pore channel activity of Nuclear Pore Complex (NPC) [nuclear envelope]
(input)	[Reaction:R-RNO-2990882] CDK1 phosphorylates NUP98
(output)	[Reaction:R-RNO-75098] mRNP complex dissociates from cytosolic face of NPC
(hasComponent)	[Complex:R-RNO-113815] NPC:NXF1,2:NXT1:EJC:CBC:mRNA [nucleoplasm] [Complex:R-RNO-159259] NPC:NXF1:NXT1:EJC:CBC:mRNA [cytosol]
(regulator)	[Requirement:10109439] Requirement by 'Nuclear Pore Complex (NPC) [nuclear envelope]'
(inferredTo)	[Complex:R-HSA-157689] Nuclear Pore Complex (NPC) [nuclear envelope]

© 2026 Reactome

Cite Us!