Reactome | PRKCB (PKC-beta) phosphorylates CARMA1

Schema > BlackBoxEvent > Entries

PRKCB (PKC-beta) phosphorylates CARMA1 Show undefined attributes

catalystActivity	[CatalystActivity:10151131] protein serine/threonine kinase activity of Activated PKC beta [plasma membrane]
category	omitted
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10151133
displayName	PRKCB (PKC-beta) phosphorylates CARMA1
eventOf	[Pathway:R-RNO-1169091] Activation of NF-kappaB in B cells - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-RNO-1168644] CARMA1 recruits MALT1 and BCL10 forming CBM Complex - Rattus norvegicus
inferredFrom	[BlackBoxEvent:R-HSA-1168635] PRKCB (PKC-beta) phosphorylates CARMA1 - Homo sapiens
input	6 × [SimpleEntity:R-ALL-113592] ATP [cytosol] [Complex:R-RNO-1169088] CARMA1 oligomer [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	PRKCB (PKC-beta) phosphorylates CARMA1
output	6 × [SimpleEntity:R-ALL-29370] ADP [cytosol] [Complex:R-RNO-1168616] p-CARMA1 Oligomer [plasma membrane]
precedingEvent	[Reaction:R-RNO-1168373] PRKCB (Protein kinase C beta, PKC-beta) binds diacylglycerol and phosphatidylserine - Rattus norvegicus
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:48895] Rattus norvegicus
stId	R-RNO-1168635
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-1169091] Activation of NF-kappaB in B cells
(precedingEvent)	[Reaction:R-RNO-1168644] CARMA1 recruits MALT1 and BCL10 forming CBM Complex
(inferredTo)	[BlackBoxEvent:R-HSA-1168635] PRKCB (PKC-beta) phosphorylates CARMA1

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