Reactome | Maturation of TCA enzymes and regulation of TCA cycle

Schema > Pathway > Entries

compartment	[Compartment:5462] mitochondrion
created	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
dbId	11129312
displayName	Maturation of TCA enzymes and regulation of TCA cycle
eventOf	[Pathway:R-PFA-71403] Citric acid cycle (TCA cycle) - Plasmodium falciparum
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	true
hasEHLD	false
hasEvent	[Reaction:R-PFA-9854315] CSKMT methylates Citrate Synthase - Plasmodium falciparum [Reaction:R-PFA-9854415] ACAT1 tetramer acetylates IDH2 dimer - Plasmodium falciparum
inferredFrom	[Pathway:R-HSA-9854311] Maturation of TCA enzymes and regulation of TCA cycle - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Maturation of TCA enzymes and regulation of TCA cycle
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:170928] Plasmodium falciparum
stId	R-PFA-9854311
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEncapsulatedEvent)	[Pathway:R-PFA-611105] Respiratory electron transport
(hasEvent)	[Pathway:R-PFA-71403] Citric acid cycle (TCA cycle)
(inferredTo)	[Pathway:R-HSA-9854311] Maturation of TCA enzymes and regulation of TCA cycle

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