Reactome | CHEK1 phosphorylates RAD51

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CHEK1 phosphorylates RAD51 Show undefined attributes

catalystActivity	[CatalystActivity:11119780] protein serine/threonine kinase activity of p-S317,S345-CHEK1 [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
dbId	11119782
displayName	CHEK1 phosphorylates RAD51
eventOf	[Pathway:R-PFA-5693616] Presynaptic phase of homologous DNA pairing and strand exchange - Plasmodium falciparum
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-5685230] CHEK1 phosphorylates RAD51 - Homo sapiens
input	[SimpleEntity:R-ALL-29358] ATP [nucleoplasm] [EntityWithAccessionedSequence:R-PFA-62637] RAD51 [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	CHEK1 phosphorylates RAD51
output	[SimpleEntity:R-ALL-113582] ADP [nucleoplasm] [EntityWithAccessionedSequence:R-PFA-5685231] phospho-p-T309-RAD51 [nucleoplasm]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:170928] Plasmodium falciparum
stId	R-PFA-5685230
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-PFA-5693616] Presynaptic phase of homologous DNA pairing and strand exchange
(inferredTo)	[Reaction:R-HSA-5685230] CHEK1 phosphorylates RAD51