Reactome | TCR signaling

Schema > Pathway > Entries

created	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
dbId	11128522
displayName	TCR signaling
eventOf	[Pathway:R-PFA-1280218] Adaptive Immune System - Plasmodium falciparum
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:161692] T cell receptor signaling pathway
hasDiagram	true
hasEHLD	false
hasEvent	[Pathway:R-PFA-202433] Generation of second messenger molecules - Plasmodium falciparum [Pathway:R-PFA-202424] Downstream TCR signaling - Plasmodium falciparum
inferredFrom	[Pathway:R-HSA-202403] TCR signaling - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	3
name	TCR signaling
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:170928] Plasmodium falciparum
stId	R-PFA-202403
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEncapsulatedEvent)	[Pathway:R-PFA-1483255] PI Metabolism [Pathway:R-PFA-389948] Co-inhibition by PD-1 [Pathway:R-PFA-1257604] PIP3 activates AKT signaling
(hasEvent)	[Pathway:R-PFA-1280218] Adaptive Immune System
(inferredTo)	[Pathway:R-HSA-202403] TCR signaling