Reactome | FDPS dimer transfers IPPP to GPP

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FDPS dimer transfers IPPP to GPP Show undefined attributes

catalystActivity	[CatalystActivity:11112363] (2E,6E)-farnesyl diphosphate synthase activity of holo-FDPS dimer [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
dbId	11112365
displayName	FDPS dimer transfers IPPP to GPP
eventOf	[Pathway:R-PFA-9969896] Lanosterol biosynthesis - Plasmodium falciparum
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-191303] FDPS dimer transfers IPPP to GPP - Homo sapiens
input	[SimpleEntity:R-ALL-191409] GPP [cytosol] [SimpleEntity:R-ALL-191362] IPPP [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	FDPS dimer transfers IPPP to GPP isopentenyl diphosphate + (2E)-geranyl diphosphate => (2E,6E)-farnesyl diphosphate + diphosphate Another isopentenyl pyrophosphate is added to geranyl pyrophosphate
output	[SimpleEntity:R-ALL-191385] FAPP [cytosol] [SimpleEntity:R-ALL-111294] PPi [cytosol]
precedingEvent	[Reaction:R-PFA-191322] FDPS dimer transfers IPPP to DMAPP - Plasmodium falciparum
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:170928] Plasmodium falciparum
stId	R-PFA-191303
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-PFA-9969896] Lanosterol biosynthesis
(inferredTo)	[Reaction:R-HSA-191303] FDPS dimer transfers IPPP to GPP

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