Reactome | FDPS dimer transfers IPPP to DMAPP

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FDPS dimer transfers IPPP to DMAPP Show undefined attributes

catalystActivity	[CatalystActivity:11112366] dimethylallyltranstransferase activity of holo-FDPS dimer [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
dbId	11112368
displayName	FDPS dimer transfers IPPP to DMAPP
eventOf	[Pathway:R-PFA-9969896] Lanosterol biosynthesis - Plasmodium falciparum
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-PFA-191303] FDPS dimer transfers IPPP to GPP - Plasmodium falciparum
inferredFrom	[Reaction:R-HSA-191322] FDPS dimer transfers IPPP to DMAPP - Homo sapiens
input	[SimpleEntity:R-ALL-191324] DMAPP [cytosol] [SimpleEntity:R-ALL-191362] IPPP [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	FDPS dimer transfers IPPP to DMAPP isopentenyl diphosphate + dimethylallyl diphosphate => (2E)-geranyl diphosphate + diphosphate Addition of isopentenyl pyrophosphate to DMAPP
output	[SimpleEntity:R-ALL-191409] GPP [cytosol] [SimpleEntity:R-ALL-111294] PPi [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:170928] Plasmodium falciparum
stId	R-PFA-191322
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-PFA-9969896] Lanosterol biosynthesis
(precedingEvent)	[Reaction:R-PFA-191303] FDPS dimer transfers IPPP to GPP
(inferredTo)	[Reaction:R-HSA-191322] FDPS dimer transfers IPPP to DMAPP

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