Reactome | DARPP-32 events

Schema > Pathway > Entries

created	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
dbId	11128350
displayName	DARPP-32 events
eventOf	[Pathway:R-PFA-111885] Opioid Signalling - Plasmodium falciparum
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-PFA-8951727] cAMP binds PKA tetramer - Plasmodium falciparum [Reaction:R-PFA-111925] cAMP induces dissociation of inactive PKA tetramers - Plasmodium falciparum
inferredFrom	[Pathway:R-HSA-180024] DARPP-32 events - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	DARPP-32 events
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:170928] Plasmodium falciparum
stId	R-PFA-180024
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-PFA-111885] Opioid Signalling
(inferredTo)	[Pathway:R-HSA-180024] DARPP-32 events