Reactome | Ub [cytosol]

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Ub [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-PFA-8864229] Ub:E2 (UBA6 substrate) [cytosol] - Plasmodium falciparum [Complex:R-PFA-6782592] UCHL1,UCHL3:Ub [cytosol] - Plasmodium falciparum
consumedByEvent	[BlackBoxEvent:R-PFA-450580] AUF1 (hnRNP D0) is ubiquitinylated - Plasmodium falciparum [BlackBoxEvent:R-PFA-450580] AUF1 (hnRNP D0) is ubiquitinylated - Plasmodium falciparum [BlackBoxEvent:R-PFA-450580] AUF1 (hnRNP D0) is ubiquitinylated - Plasmodium falciparum [BlackBoxEvent:R-PFA-450580] AUF1 (hnRNP D0) is ubiquitinylated - Plasmodium falciparum [Reaction:R-PFA-8852132] Ub-Cys632-UBA1 adenylates ubiquitin in the cytosol - Plasmodium falciparum [Reaction:R-PFA-174159] Ubiquitination of Emi1 by SCF-beta-TrCP - Plasmodium falciparum [Reaction:R-PFA-174159] Ubiquitination of Emi1 by SCF-beta-TrCP - Plasmodium falciparum [Reaction:R-PFA-174159] Ubiquitination of Emi1 by SCF-beta-TrCP - Plasmodium falciparum [Reaction:R-PFA-983153] E1 mediated ubiquitin activation - Plasmodium falciparum [BlackBoxEvent:R-PFA-9688831] STUB1 ubiquitinates RIPK3 at K55, K363 - Plasmodium falciparum [Reaction:R-PFA-8848829] CBL autoubiquitinates - Plasmodium falciparum [Reaction:R-PFA-8848829] CBL autoubiquitinates - Plasmodium falciparum [Reaction:R-PFA-8848829] CBL autoubiquitinates - Plasmodium falciparum [Reaction:R-PFA-1504190] DVL is ubiquitinated by CUL3:KLHL12:RBX1 - Plasmodium falciparum [Reaction:R-PFA-8854041] SCF-FBXL7 ubiquitinates AURKA - Plasmodium falciparum [Reaction:R-PFA-8854041] SCF-FBXL7 ubiquitinates AURKA - Plasmodium falciparum [Reaction:R-PFA-8854041] SCF-FBXL7 ubiquitinates AURKA - Plasmodium falciparum [Reaction:R-PFA-9929350] Ubiquitination of CD274 by BTRC-SCF E3-ligase complex - Plasmodium falciparum [Reaction:R-PFA-9929350] Ubiquitination of CD274 by BTRC-SCF E3-ligase complex - Plasmodium falciparum [Reaction:R-PFA-9929350] Ubiquitination of CD274 by BTRC-SCF E3-ligase complex - Plasmodium falciparum [Reaction:R-PFA-5691108] SKP1:FBXL5:CUL1:NEDD8 ubiquitinylates IREB2 - Plasmodium falciparum [Reaction:R-PFA-5691108] SKP1:FBXL5:CUL1:NEDD8 ubiquitinylates IREB2 - Plasmodium falciparum [Reaction:R-PFA-5691108] SKP1:FBXL5:CUL1:NEDD8 ubiquitinylates IREB2 - Plasmodium falciparum [Reaction:R-PFA-9755505] KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 - Plasmodium falciparum [Reaction:R-PFA-9755505] KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 - Plasmodium falciparum [Reaction:R-PFA-9755505] KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 - Plasmodium falciparum [Reaction:R-PFA-9759172] KEAP1:CUL3:RBX1 ubiquitinates p-S349 SQSTM1 oligomer - Plasmodium falciparum [Reaction:R-PFA-9759172] KEAP1:CUL3:RBX1 ubiquitinates p-S349 SQSTM1 oligomer - Plasmodium falciparum [Reaction:R-PFA-9759172] KEAP1:CUL3:RBX1 ubiquitinates p-S349 SQSTM1 oligomer - Plasmodium falciparum [Reaction:R-PFA-8852134] UBA1 adenylates ubiquitin in the cytosol - Plasmodium falciparum
created	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
dbId	11108984
displayName	Ub [cytosol]
hasMember	[DefinedSet:R-PFA-939205-3] Homologues of RPS27A(1-76) [cytosol] - Plasmodium falciparum [DefinedSet:R-PFA-939213-3] Homologues of UBB(77-152) [cytosol] - Plasmodium falciparum [DefinedSet:R-PFA-939230-3] Homologues of UBB(153-228) [cytosol] - Plasmodium falciparum [DefinedSet:R-PFA-939188-2] Homologues of UBC(1-76) [cytosol] - Plasmodium falciparum [DefinedSet:R-PFA-939164-2] Homologues of UBC(77-152) [cytosol] - Plasmodium falciparum [DefinedSet:R-PFA-939258-2] Homologues of UBC(153-228) [cytosol] - Plasmodium falciparum [DefinedSet:R-PFA-939192-4] Homologues of UBC(229-304) [cytosol] - Plasmodium falciparum [DefinedSet:R-PFA-939232-4] Homologues of UBC(305-380) [cytosol] - Plasmodium falciparum [DefinedSet:R-PFA-939191-4] Homologues of UBC(381-456) [cytosol] - Plasmodium falciparum [DefinedSet:R-PFA-939184-4] Homologues of UBC(457-532) [cytosol] - Plasmodium falciparum [DefinedSet:R-PFA-939239-4] Homologues of UBC(533-608) [cytosol] - Plasmodium falciparum [DefinedSet:R-PFA-939165-4] Homologues of UBC(609-684) [cytosol] - Plasmodium falciparum
inDisease	false
inferredFrom	[DefinedSet:R-HSA-113595] Ub [cytosol] - Homo sapiens
maxDepth	3
name	Ub ubiquitin
producedByEvent	[BlackBoxEvent:R-PFA-450466] AUF1:mRNA complex is degraded - Plasmodium falciparum [BlackBoxEvent:R-PFA-450466] AUF1:mRNA complex is degraded - Plasmodium falciparum [BlackBoxEvent:R-PFA-450466] AUF1:mRNA complex is degraded - Plasmodium falciparum [BlackBoxEvent:R-PFA-450466] AUF1:mRNA complex is degraded - Plasmodium falciparum [BlackBoxEvent:R-PFA-450466] AUF1:mRNA complex is degraded - Plasmodium falciparum [BlackBoxEvent:R-PFA-450466] AUF1:mRNA complex is degraded - Plasmodium falciparum [BlackBoxEvent:R-PFA-450466] AUF1:mRNA complex is degraded - Plasmodium falciparum [BlackBoxEvent:R-PFA-450466] AUF1:mRNA complex is degraded - Plasmodium falciparum [BlackBoxEvent:R-PFA-450466] AUF1:mRNA complex is degraded - Plasmodium falciparum [BlackBoxEvent:R-PFA-450466] AUF1:mRNA complex is degraded - Plasmodium falciparum [BlackBoxEvent:R-PFA-450466] AUF1:mRNA complex is degraded - Plasmodium falciparum [BlackBoxEvent:R-PFA-450466] AUF1:mRNA complex is degraded - Plasmodium falciparum [BlackBoxEvent:R-PFA-9954728] The proteasome degrades the K48-polyubiquitinated alanine-tailed nascent peptide - Plasmodium falciparum [BlackBoxEvent:R-PFA-9954728] The proteasome degrades the K48-polyubiquitinated alanine-tailed nascent peptide - Plasmodium falciparum [BlackBoxEvent:R-PFA-9954728] The proteasome degrades the K48-polyubiquitinated alanine-tailed nascent peptide - Plasmodium falciparum [Reaction:R-PFA-8865182] OTUD7A hydrolyses K11diUb - Plasmodium falciparum [Reaction:R-PFA-8865182] OTUD7A hydrolyses K11diUb - Plasmodium falciparum [BlackBoxEvent:R-PFA-174203] SCF-mediated degradation of Emi1 - Plasmodium falciparum [BlackBoxEvent:R-PFA-174203] SCF-mediated degradation of Emi1 - Plasmodium falciparum [BlackBoxEvent:R-PFA-174203] SCF-mediated degradation of Emi1 - Plasmodium falciparum [BlackBoxEvent:R-PFA-174203] SCF-mediated degradation of Emi1 - Plasmodium falciparum [BlackBoxEvent:R-PFA-983150] Proteasomal cleavage of substrate - Plasmodium falciparum [BlackBoxEvent:R-PFA-68948] Ubiquitinated Orc1 is degraded by the proteasome - Plasmodium falciparum [BlackBoxEvent:R-PFA-68948] Ubiquitinated Orc1 is degraded by the proteasome - Plasmodium falciparum [BlackBoxEvent:R-PFA-68948] Ubiquitinated Orc1 is degraded by the proteasome - Plasmodium falciparum [BlackBoxEvent:R-PFA-69016] Ubiquitinated Cdc6 is degraded by the proteasome - Plasmodium falciparum [Reaction:R-PFA-9929352] Ubiquitinated CD274 is degraded by the 26S proteasome - Plasmodium falciparum [Reaction:R-PFA-9929352] Ubiquitinated CD274 is degraded by the 26S proteasome - Plasmodium falciparum [Reaction:R-PFA-9929352] Ubiquitinated CD274 is degraded by the 26S proteasome - Plasmodium falciparum [BlackBoxEvent:R-PFA-8866553] misfolded CFTR is degraded by the 26S proteasome - Plasmodium falciparum [BlackBoxEvent:R-PFA-9755306] ub UBXN7 is degraded by the 26S proteasome - Plasmodium falciparum [BlackBoxEvent:R-PFA-1504193] Ubiquitinated DVL is degraded by the proteasome - Plasmodium falciparum [BlackBoxEvent:R-PFA-8854044] Proteasome degrades AURKA ubiquitinated by SCF-FBXL7 - Plasmodium falciparum [BlackBoxEvent:R-PFA-8854044] Proteasome degrades AURKA ubiquitinated by SCF-FBXL7 - Plasmodium falciparum [BlackBoxEvent:R-PFA-8854044] Proteasome degrades AURKA ubiquitinated by SCF-FBXL7 - Plasmodium falciparum
schemaClass	DefinedSet
species	[Species:170928] Plasmodium falciparum
stId	R-PFA-113595

Referrals

(hasComponent)	[Complex:R-PFA-6782592] UCHL1,UCHL3:Ub [cytosol] [Complex:R-PFA-8864229] Ub:E2 (UBA6 substrate) [cytosol] [Complex:R-PFA-8852066] Ub-Cys625-UBA6 [cytosol] [Complex:R-PFA-8852251] Ub:E2 (UBA1 substrate) [cytosol] [Complex:R-PFA-8852063] Ub-Cys632-UBA1 [cytosol] [Complex:R-PFA-8866534] Ub-misfolded nascent CFTR [cytosol] [Complex:R-PFA-9640491] Ub:UBE2N:UBE2V1 [cytosol] [Complex:R-PFA-9835021] Ub:Ub-UBE2D2,UBE2D3,UBE2N:UBE2V1,UBE2L3 [cytosol] [Complex:R-PFA-174061] SCF-associated multiubiquitinated Emi1complexes [cytosol] [Complex:R-PFA-983130] Ub:substrate [cytosol] [Complex:R-PFA-976165] Ubiquitin:E2 conjugating enzymes [cytosol] [Complex:R-PFA-976164] E1 bound ubiquitin [cytosol] [Complex:R-PFA-1234116] UBE2D1,2,3:Ubiquitin [cytosol] [Complex:R-PFA-8937453] Ub:UBE2D3 [cytosol] [Complex:R-PFA-8938763] Ub:UBE2L3 [cytosol] [Complex:R-PFA-68570] ubiquitinated Cdc6 [cytosol] [Complex:R-PFA-204940] K63 linked polyubiquitin chain [cytosol] [Complex:R-PFA-8866894] Ub-unfolded protein:(GlcNAc)2 (Man)9-5 [cytosol] [Complex:R-PFA-8867287] Ub-unfolded protein:(GlcNAc)2 (Man)9-5 [endoplasmic reticulum quality control compartment] [Complex:R-PFA-9929359] polyUb-p184,T189-CD274:BTRC E3 complex [cytosol]
(input)	[BlackBoxEvent:R-PFA-450580] AUF1 (hnRNP D0) is ubiquitinylated [Reaction:R-PFA-8852132] Ub-Cys632-UBA1 adenylates ubiquitin in the cytosol [Reaction:R-PFA-8852134] UBA1 adenylates ubiquitin in the cytosol [Reaction:R-PFA-174159] Ubiquitination of Emi1 by SCF-beta-TrCP [Reaction:R-PFA-983153] E1 mediated ubiquitin activation [BlackBoxEvent:R-PFA-9688831] STUB1 ubiquitinates RIPK3 at K55, K363 [Reaction:R-PFA-8848829] CBL autoubiquitinates [Reaction:R-PFA-1504190] DVL is ubiquitinated by CUL3:KLHL12:RBX1 [Reaction:R-PFA-8854041] SCF-FBXL7 ubiquitinates AURKA [Reaction:R-PFA-9929350] Ubiquitination of CD274 by BTRC-SCF E3-ligase complex [Reaction:R-PFA-5691108] SKP1:FBXL5:CUL1:NEDD8 ubiquitinylates IREB2 [Reaction:R-PFA-9755505] KEAP1:NEDD8-CUL3:RBX1 complex ubiquitinates NFE2L2 [Reaction:R-PFA-9759172] KEAP1:CUL3:RBX1 ubiquitinates p-S349 SQSTM1 oligomer
(output)	[BlackBoxEvent:R-PFA-450466] AUF1:mRNA complex is degraded [BlackBoxEvent:R-PFA-9954728] The proteasome degrades the K48-polyubiquitinated alanine-tailed nascent peptide [Reaction:R-PFA-8865182] OTUD7A hydrolyses K11diUb [BlackBoxEvent:R-PFA-174203] SCF-mediated degradation of Emi1 [BlackBoxEvent:R-PFA-983150] Proteasomal cleavage of substrate [BlackBoxEvent:R-PFA-68948] Ubiquitinated Orc1 is degraded by the proteasome [BlackBoxEvent:R-PFA-1504193] Ubiquitinated DVL is degraded by the proteasome [BlackBoxEvent:R-PFA-69016] Ubiquitinated Cdc6 is degraded by the proteasome [BlackBoxEvent:R-PFA-8854044] Proteasome degrades AURKA ubiquitinated by SCF-FBXL7 [Reaction:R-PFA-9929352] Ubiquitinated CD274 is degraded by the 26S proteasome [BlackBoxEvent:R-PFA-8866553] misfolded CFTR is degraded by the 26S proteasome [BlackBoxEvent:R-PFA-9755306] ub UBXN7 is degraded by the 26S proteasome
(inferredTo)	[DefinedSet:R-HSA-113595] Ub [cytosol]

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