Reactome | IFIH1 ligand [cytosol]

Schema > DefinedSet > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-913727] viral dsRNA:IFIH1 [cytosol] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-913725] viral dsRNA binds IFIH1:TKFC - Homo sapiens
created	[InstanceEdit:9038421] Shamovsky, Veronica, 2018-02-26
crossReference	[DatabaseIdentifier:12020762] Mondo:0005108
dbId	9038422
deleted	[Deleted:9038427] Deletion of instance: 9013950
disease	[Disease:3134794] viral infectious disease
displayName	IFIH1 ligand [cytosol]
goCellularComponent	[Compartment:436407] host cell cytosol
hasMember	[GenomeEncodedEntity:R-MVI-9013943] MV dsRNA intermediate form [cytosol] - Measles virus [GenomeEncodedEntity:R-FLU-6790580] Influenza A dsRNA intermediate form [cytosol] - Influenza A virus [GenomeEncodedEntity:R-RSY-9835308] RSV A dsRNA intermediate form [cytosol] - Human respiratory syncytial virus A
inDisease	true
literatureReference	[LiteratureReference:9013945] The interferon-inducible RNA helicase, mda-5, is involved in measles virus-induced expression of antiviral cytokines
maxDepth	2
modified	[InstanceEdit:9983308] Weiser, Joel, 2026-02-22
name	IFIH1 ligand MDA5 ligand
schemaClass	DefinedSet
species	[Species:9013948] Measles virus [Species:9031716] Influenza A virus [Species:9717528] Human respiratory syncytial virus A
stId	R-NUL-9038422
updateTrackers	[UpdateTracker:9905899] Update Tracker - [DefinedSet:9038422] IFIH1 ligand [cytosol] - v85:[addHasMember, addSpecies]

(updatedInstance)	[UpdateTracker:9905899] Update Tracker - [DefinedSet:9038422] IFIH1 ligand [cytosol] - v85:[addHasMember, addSpecies]
(replacementInstances)	[Deleted:9038427] Deletion of instance: 9013950
(input)	[Reaction:R-HSA-913725] viral dsRNA binds IFIH1:TKFC
(hasComponent)	[Complex:R-HSA-913727] viral dsRNA:IFIH1 [cytosol]

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