Reactome | DNA-PK ligands [cytosol]

Schema > DefinedSet > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-3134811] DNA-PK:microbial dsDNA [cytosol] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-3134821] DNA-PK binds microbial dsDNA - Homo sapiens
created	[InstanceEdit:9013762] Shamovsky, Veronica, 2017-07-26
crossReference	[DatabaseIdentifier:12020762] Mondo:0005108
dbId	9013760
deleted	[Deleted:9014391] Deletion of instance: 3134797
disease	[Disease:3134794] viral infectious disease
displayName	DNA-PK ligands [cytosol]
goCellularComponent	[Compartment:436407] host cell cytosol
hasMember	[GenomeEncodedEntity:R-HBV-9013761] HBV dsDNA [cytosol] - Hepatitis B virus [GenomeEncodedEntity:R-VVI-9013755] VACV dsDNA [cytosol] - Vaccinia virus
inDisease	true
literatureReference	[LiteratureReference:9013763] Cytoplasm-Translocated Ku70/80 Complex Sensing of HBV DNA Induces Hepatitis-Associated Chemokine Secretion [LiteratureReference:9013764] A mechanism for the inhibition of DNA-PK-mediated DNA sensing by a virus
maxDepth	2
modified	[InstanceEdit:9983308] Weiser, Joel, 2026-02-22
name	DNA-PK ligands
schemaClass	DefinedSet
species	[Species:2671785] Vaccinia virus [Species:5229092] Hepatitis B virus
stId	R-NUL-9013760

(replacementInstances)	[Deleted:9014391] Deletion of instance: 3134797
(input)	[Reaction:R-HSA-3134821] DNA-PK binds microbial dsDNA
(hasComponent)	[Complex:R-HSA-3134811] DNA-PK:microbial dsDNA [cytosol]

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