Reactome | frog CK1gamma phosphorylates LRP5/6

Schema > Reaction > Entries

frog CK1gamma phosphorylates LRP5/6 Show undefined attributes

authored	[InstanceEdit:3640727] Rothfels, K, 2013-05-29
catalystActivity	[CatalystActivity:208882] protein serine/threonine kinase activity of CKIgamma [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol [Compartment:984] extracellular region
created	[InstanceEdit:1458903] Rothfels, K, 2011-07-22
dbId	1458902
displayName	frog CK1gamma phosphorylates LRP5/6
edited	[InstanceEdit:4655138] Gillespie, ME, 2013-10-02
input	5 × [SimpleEntity:R-ALL-113592] ATP [cytosol] [Complex:R-HSA-1458897] WNT:FZD:p5S/T-LRP5/6:DVL:AXIN:GSK3B [plasma membrane]
isChimeric	true
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:208206] Casein kinase 1 gamma couples Wnt receptor activation to cytoplasmic signal transduction
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	frog CK1gamma phosphorylates LRP5/6
orthologousEvent	[Reaction:R-HSA-201691] Phosphorylation of LRP5/6 cytoplasmic domain by CSNKI - Homo sapiens
output	5 × [SimpleEntity:R-ALL-29370] ADP [cytosol] [Complex:R-HSA-1458890] WNT:FZD:p10S/T-LRP5/6:DVL:AXIN:GSK3B [plasma membrane]
releaseDate	2014-03-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:5251465] Rajakulendran, Nishani, 2014-01-22 [InstanceEdit:5323527] van Amerongen, R, 2014-02-14 [InstanceEdit:5368564] Kikuchi, Akira, 2014-04-22
schemaClass	Reaction
species	[Species:48887] Homo sapiens [Species:205621] Xenopus tropicalis
stId	R-NUL-1458902
summation	[Summation:3772426] Xenopus tropicalis Casein kinase 1 gamma was identified in a...

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