Reactome | WNT:FZD:p10S/T-LRP5/6:DVL:AXIN:GSK3B [plasma membrane]

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WNT:FZD:p10S/T-LRP5/6:DVL:AXIN:GSK3B [plasma membrane] Show undefined attributes

compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:1458892] Rothfels, K, 2011-07-22
dbId	1458890
displayName	WNT:FZD:p10S/T-LRP5/6:DVL:AXIN:GSK3B [plasma membrane]
hasComponent	[DefinedSet:R-HSA-1504202] canonical FZD receptors [plasma membrane] [DefinedSet:R-HSA-1504197] canonical WNTs [extracellular region] [Complex:R-HSA-1504204] GSK3B:AXIN1 [cytosol] [DefinedSet:R-HSA-1458891] p10S/T-LRP5/6 [plasma membrane] [DefinedSet:R-HSA-3772407] pp-DVL [cytosol]
inDisease	false
includedLocation	[Compartment:70101] cytosol [Compartment:984] extracellular region
inferredTo	[Complex:R-MMU-1458890] WNT:FZD:p10S/T-LRP5/6:DVL:AXIN:GSK3B [plasma membrane] - Mus musculus [Complex:R-RNO-1458890] WNT:FZD:p10S/T-LRP5/6:DVL:AXIN:GSK3B [plasma membrane] - Rattus norvegicus [Complex:R-CFA-1458890] WNT:FZD:p10S/T-LRP5/6:DVL:AXIN:GSK3B [plasma membrane] - Canis familiaris [Complex:R-BTA-1458890] WNT:FZD:p10S/T-LRP5/6:DVL:AXIN:GSK3B [plasma membrane] - Bos taurus [Complex:R-SSC-1458890] WNT:FZD:p10S/T-LRP5/6:DVL:AXIN:GSK3B [plasma membrane] - Sus scrofa
isChimeric	false
modified	[InstanceEdit:3772511] Rothfels, K, 2013-06-25
name	WNT:FZD:p10S/T-LRP5/6:DVL:AXIN:GSK3B
positivelyRegulates	[PositiveRegulation:R-HSA-8981436] Positive regulation by 'WNT:FZD:p10S/T-LRP5/6:DVL:AXIN:GSK3B [plasma membrane]'
producedByEvent	[Reaction:R-HSA-201691] Phosphorylation of LRP5/6 cytoplasmic domain by CSNKI - Homo sapiens [Reaction:R-NUL-1458902] frog CK1gamma phosphorylates LRP5/6 - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-1458890

Referrals

(output)	[Reaction:R-NUL-1458902] frog CK1gamma phosphorylates LRP5/6 [Reaction:R-HSA-201691] Phosphorylation of LRP5/6 cytoplasmic domain by CSNKI
(regulator)	[PositiveRegulation:R-HSA-8981436] Positive regulation by 'WNT:FZD:p10S/T-LRP5/6:DVL:AXIN:GSK3B [plasma membrane]'

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