Reactome | p-Y641-Stat6 dimer [nucleoplasm]

Schema > Complex > Entries

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-MMU-9977980] Mll1:Men1:p-Y641-Stat6:p-S245-Nfatc2:Notch1,2 Coactivator:Gata3 gene [nucleoplasm] - Mus musculus [Complex:R-MMU-9977961] Gata3:Yy1:Ets1:Pou2f1:Pou2f2:Batf:Irf4:Satb1:Smarca4:p-Y641-Stat6:Rad50 gene [nucleoplasm] - Mus musculus
consumedByEvent	[Reaction:R-MMU-9977982] Gata3, Yy1, Ets1, Pou2f1, Pou2f2, Batf, Irf4, Satb1, Smarca4 and Stat6 bind the Locus Control Region in the Rad50 gene - Mus musculus [Reaction:R-MMU-9977960] Stat6, Nfatc2 (Nfat1), and Nicd1,2 bind the Gata3 gene and cause displacement of repressor complexes (Prc1, Rbpj:NcoR) by activator complexes (Mll1, Rbpj:Nicd1,2) - Mus musculus
created	[InstanceEdit:9978007] May, Bruce, 2025-12-27
dbId	9977972
displayName	p-Y641-Stat6 dimer [nucleoplasm]
hasComponent	2 × [EntityWithAccessionedSequence:R-MMU-9967194] p-Y641-Stat6 [nucleoplasm]
inDisease	false
isChimeric	false
maxDepth	2
name	p-Y641-Stat6 dimer
schemaClass	Complex
species	[Species:48892] Mus musculus
stId	R-MMU-9977972

(hasComponent)	[Complex:R-MMU-9977961] Gata3:Yy1:Ets1:Pou2f1:Pou2f2:Batf:Irf4:Satb1:Smarca4:p-Y641-Stat6:Rad50 gene [nucleoplasm] [Complex:R-MMU-9977980] Mll1:Men1:p-Y641-Stat6:p-S245-Nfatc2:Notch1,2 Coactivator:Gata3 gene [nucleoplasm]
(input)	[Reaction:R-MMU-9977982] Gata3, Yy1, Ets1, Pou2f1, Pou2f2, Batf, Irf4, Satb1, Smarca4 and Stat6 bind the Locus Control Region in the Rad50 gene [Reaction:R-MMU-9977960] Stat6, Nfatc2 (Nfat1), and Nicd1,2 bind the Gata3 gene and cause displacement of repressor complexes (Prc1, Rbpj:NcoR) by activator complexes (Mll1, Rbpj:Nicd1,2)
(activeUnit)	[PositiveGeneExpressionRegulation:9977995] Positive gene expression regulation by 'Mll1:Men1:p-Y641-Stat6:p-S245-Nfatc2:Notch1,2 Coactivator:Gata3 gene [nucleoplasm]'