Reactome | Positive gene expression regulation by 'Mll1:Men1:p-Y641-Stat6:p-S245-Nfatc2:Notch1,2 Coactivator:Gata3 gene [nucleoplasm]'

Schema > PositiveGeneExpressionRegulation > Entries

activeUnit	[EntityWithAccessionedSequence:R-MMU-2025858] p-S245-Nfatc2 [nucleoplasm] - Mus musculus [Complex:R-MMU-9977972] p-Y641-Stat6 dimer [nucleoplasm] - Mus musculus [Complex:R-MMU-9977969] Nicd1,2:Rbpj:Snw1 [nucleoplasm] - Mus musculus
activity	[GO_MolecularFunction:1042306] DNA-binding transcription factor activity, RNA polymerase II-specific
created	[InstanceEdit:9978007] May, Bruce, 2025-12-27
dbId	9977995
displayName	Positive gene expression regulation by 'Mll1:Men1:p-Y641-Stat6:p-S245-Nfatc2:Notch1,2 Coactivator:Gata3 gene [nucleoplasm]'
regulatedEntity	[BlackBoxEvent:R-MMU-9977991] Stat6, Nfatc2, and Nicd1,2 positiively regulate expression of Gata3 - Mus musculus
regulator	[Complex:R-MMU-9977980] Mll1:Men1:p-Y641-Stat6:p-S245-Nfatc2:Notch1,2 Coactivator:Gata3 gene [nucleoplasm]
schemaClass	PositiveGeneExpressionRegulation

(regulation)	[RegulationReference:9977971] Positive gene expression regulation by 'Mll1:Men1:p-Y641-Stat6:p-S245-Nfatc2:Notch1,2 Coactivator:Gata3 gene [nucleoplasm]' STAT6-mediated displacement of polycomb by trithorax complex establishes long-term maintenance of GATA3 expression in T helper type 2 cells
(regulatedBy)	[BlackBoxEvent:R-MMU-9977991] Stat6, Nfatc2, and Nicd1,2 positiively regulate expression of Gata3

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