Reactome | p-S-Cry:p-S-Per:Csnk1d,e:p-S90,Ac-538-Bmal1:p-4S,2T-Clock dissociates from target gene

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p-S-Cry:p-S-Per:Csnk1d,e:p-S90,Ac-538-Bmal1:p-4S,2T-Clock dissociates from target gene Show undefined attributes

authored	[InstanceEdit:9927978] May, Bruce, 2024-11-10
category	dissociation
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9927979] May, Bruce, 2024-11-11
dbId	9927991
displayName	p-S-Cry:p-S-Per:Csnk1d,e:p-S90,Ac-538-Bmal1:p-4S,2T-Clock dissociates from target gene
edited	[InstanceEdit:9927978] May, Bruce, 2024-11-10
input	[Complex:R-MMU-9927981] p-S-Cry:p-S-Per:Csnk1d,e:p-S97,Ac-K544-Bmal1:p-S,T451,T461,S440,S441,S446-Clock:Nr1d1 gene [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9927995] Molecular mechanism of the repressive phase of the mammalian circadian clock [LiteratureReference:9927975] Dual modes of CLOCK:BMAL1 inhibition mediated by Cryptochrome and Period proteins in the mammalian circadian clock [LiteratureReference:9036813] Mammalian Period represses and de-represses transcription by displacing CLOCK-BMAL1 from promoters in a Cryptochrome-dependent manner
maxDepth	1
modified	[InstanceEdit:9938697] May, Bruce, 2025-02-18
name	p-S-Cry:p-S-Per:Csnk1d,e:p-S90,Ac-538-Bmal1:p-4S,2T-Clock dissociates from target gene
orthologousEvent	[BlackBoxEvent:R-HSA-9923005] p-S-CRY:p-S-PER:CSNK1D,E:p-S90,Ac-538-BMAL1:p-4S,2T-CLOCK dissociates from target gene - Homo sapiens
output	[EntityWithAccessionedSequence:R-MMU-5663171] Nr1d1 gene [nucleoplasm] [Complex:R-MMU-9927994] p-S-Cry:p-S-Per:Csnk1d,e:p-S97,Ac-K544-Bmal1:p-S,T451,T461,S440,S441,S446-Clock [nucleoplasm]
previousReviewStatus	[ReviewStatus:9821383] three stars
releaseDate	2025-03-26
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9938389] Sancar, Aziz, 2025-02-14 [InstanceEdit:9938694] Albrecht, Urs, 2025-02-18
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-9927991
summation	[Summation:9931516] After phosphorylation of Clock by the kinase Csnk1d, the Bma...

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