Reactome | Dis3l2 hydrolyzes uridylated mRNA

Schema > BlackBoxEvent > Entries

authored	[InstanceEdit:9822429] May, Bruce, 2022-12-23
catalystActivity	[CatalystActivity:9822435] 3'-5'-RNA exonuclease activity of Dis3l2:Pabpn1:uridylated partially deadenylated mRNA complex [cytosol]
category	omitted
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9822431] May, Bruce, 2022-12-23
dbId	9822432
displayName	Dis3l2 hydrolyzes uridylated mRNA
edited	[InstanceEdit:9822429] May, Bruce, 2022-12-23
input	[Complex:R-MMU-9820838] Dis3l2:Pabpn1:uridylated partially deadenylated mRNA complex [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9820811] Nuclear poly(A) binding protein 1 (PABPN1) mediates zygotic genome activation-dependent maternal mRNA clearance during mouse early embryonic development
maxDepth	1
modified	[InstanceEdit:9841067] May, Bruce, 2023-08-08
name	Dis3l2 hydrolyzes uridylated mRNA
orthologousEvent	[BlackBoxEvent:R-HSA-9822437] DIS3L2 hydrolyzes uridylated mRNA - Homo sapiens
output	[EntityWithAccessionedSequence:R-MMU-9820873] Dis3l2 [cytosol] [EntityWithAccessionedSequence:R-MMU-9822422] Pabpn1 [cytosol]
releaseDate	2023-09-13
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9841065] Xie, Wei, 2023-08-08
schemaClass	BlackBoxEvent
species	[Species:48892] Mus musculus
stId	R-MMU-9822432
summation	[Summation:9822433] Pabpn1 bound to 3' uridylated mRNA recruits Dis3l2, an exoso...

Cite Us!