Reactome | PAXIP1:PAGR1 complex, NCOA6 and KDM6A bind MLL3 complex

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PAXIP1:PAGR1 complex, NCOA6 and KDM6A bind MLL3 complex Show undefined attributes

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10093521
displayName	PAXIP1:PAGR1 complex, NCOA6 and KDM6A bind MLL3 complex
eventOf	[Pathway:R-MMU-9818564] Epigenetic regulation of gene expression by MLL3 and MLL4 complexes - Mus musculus [Pathway:R-MMU-9772755] Formation of WDR5-containing histone-modifying complexes - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9821412] PAXIP1:PAGR1 complex, NCOA6 and KDM6A bind MLL3 complex - Homo sapiens
input	[EntityWithAccessionedSequence:R-MMU-5617950] Kdm6a [nucleoplasm] [Complex:R-MMU-9676265] MLL3 complex [nucleoplasm] [EntityWithAccessionedSequence:R-MMU-376414] Ncoa6 [nucleoplasm] [Complex:R-MMU-9821387] PAXIP1:PAGR1 [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	PAXIP1:PAGR1 complex, NCOA6 and KDM6A bind MLL3 complex
output	[Complex:R-MMU-9821407] MLL3-ASCOM [nucleoplasm]
precedingEvent	[Reaction:R-MMU-9821395] PAXIP1 binds PAGR1 - Mus musculus [Reaction:R-MMU-9676254] Formation of the MLL3 complex - Mus musculus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-9821412
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-9818564] Epigenetic regulation of gene expression by MLL3 and MLL4 complexes [Pathway:R-MMU-9772755] Formation of WDR5-containing histone-modifying complexes
(inferredTo)	[Reaction:R-HSA-9821412] PAXIP1:PAGR1 complex, NCOA6 and KDM6A bind MLL3 complex

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