Reactome | GSK3B phosphorylates p-NFE2L2

Schema > Reaction > Entries

GSK3B phosphorylates p-NFE2L2 Show undefined attributes

catalystActivity	[CatalystActivity:182568] protein serine/threonine kinase activity of Gsk3b [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10092328
displayName	GSK3B phosphorylates p-NFE2L2
eventOf	[Pathway:R-MMU-9762114] GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-MMU-9762093] BTRC binds p-S344, 347 NFE2L2 - Mus musculus
inferredFrom	[Reaction:R-HSA-9762094] GSK3B phosphorylates p-NFE2L2 - Homo sapiens
input	[SimpleEntity:R-ALL-29358] ATP [nucleoplasm] [CandidateSet:R-MMU-9708562] p-NFE2L2 [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	GSK3B phosphorylates p-NFE2L2
output	2 × [SimpleEntity:R-ALL-113582] ADP [nucleoplasm] [CandidateSet:R-MMU-9762061] p-S344, 347 NFE2L2 [nucleoplasm]
precedingEvent	[BlackBoxEvent:R-MMU-8932309] NFE2L2 translocates from cytosol to nucleoplasm - Mus musculus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-9762094
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-9762114] GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2
(precedingEvent)	[Reaction:R-MMU-9762093] BTRC binds p-S344, 347 NFE2L2
(inferredTo)	[Reaction:R-HSA-9762094] GSK3B phosphorylates p-NFE2L2

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