Reactome | Rnf41 [cytosol]

Schema > EntityWithAccessionedSequence > Entries

candidateOf	[CandidateSet:R-MMU-976075] E3 ligases in proteasomal degradation [cytosol] - Mus musculus
catalystActivities	[CatalystActivity:10030338] ubiquitin-protein transferase activity of RNF41 [cytosol]
compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-MMU-1358734] NRG1/2:p-10Y-ERBB3:p-ERBB2:RNF41 [plasma membrane] - Mus musculus [Complex:R-MMU-1358732] ERBB3:RNF41 [plasma membrane] - Mus musculus
consumedByEvent	[Reaction:R-MMU-1358798] RNF41 binds neuregulin-activated ERBB3 - Mus musculus [Reaction:R-MMU-1358789] Self-ubiquitination of RNF41 - Mus musculus [Reaction:R-MMU-1358801] ERBB3 binds RNF41 ubiquitin ligase - Mus musculus
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10026683
displayName	Rnf41 [cytosol]
endCoordinate	317
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-975977] RNF41 [cytosol] - Homo sapiens
maxDepth	1
name	Rnf41 RNF41 Q8BH75
producedByEvent	[Reaction:R-MMU-1358795] Deubiquitination of RNF41 by P-USP8 - Mus musculus [Reaction:R-MMU-1358792] RNF41 ubiquitinates activated ERBB3 - Mus musculus [Reaction:R-MMU-1358790] RNF41 ubiquitinates ERBB3 - Mus musculus
referenceEntity	[ReferenceGeneProduct:uniprot:Q8BH75] UniProt:Q8BH75
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48892] Mus musculus
stId	R-MMU-975977
startCoordinate	1

(output)	[Reaction:R-MMU-1358795] Deubiquitination of RNF41 by P-USP8 [Reaction:R-MMU-1358790] RNF41 ubiquitinates ERBB3 [Reaction:R-MMU-1358792] RNF41 ubiquitinates activated ERBB3
(input)	[Reaction:R-MMU-1358798] RNF41 binds neuregulin-activated ERBB3 [Reaction:R-MMU-1358801] ERBB3 binds RNF41 ubiquitin ligase [Reaction:R-MMU-1358789] Self-ubiquitination of RNF41
(hasComponent)	[Complex:R-MMU-1358734] NRG1/2:p-10Y-ERBB3:p-ERBB2:RNF41 [plasma membrane] [Complex:R-MMU-1358732] ERBB3:RNF41 [plasma membrane] [Complex:R-MMU-1358737] Ub-RNF41 [cytosol]
(physicalEntity)	[CatalystActivity:10030338] ubiquitin-protein transferase activity of RNF41 [cytosol]
(hasCandidate)	[CandidateSet:R-MMU-976075] E3 ligases in proteasomal degradation [cytosol]
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-975977] RNF41 [cytosol]