Reactome | Deubiquitination of RNF41 by P-USP8

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Deubiquitination of RNF41 by P-USP8 Show undefined attributes

catalystActivity	[CatalystActivity:10030366] cysteine-type deubiquitinase activity of Ub-RNF41:p-USP8 [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10030368
displayName	Deubiquitination of RNF41 by P-USP8
eventOf	[Pathway:R-MMU-1358803] Downregulation of ERBB2:ERBB3 signaling - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-1358795] Deubiquitination of RNF41 by P-USP8 - Homo sapiens
input	[Complex:R-MMU-1358740] Ub-RNF41:p-USP8 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Deubiquitination of RNF41 by P-USP8
output	[EntityWithAccessionedSequence:R-MMU-1358714] phospho-Usp8 [cytosol] [EntityWithAccessionedSequence:R-MMU-975977] Rnf41 [cytosol] [DefinedSet:R-MMU-113595] Ub [cytosol]
precedingEvent	[Reaction:R-MMU-1358797] Ubiquitinated RNF41 binds P-USP8 - Mus musculus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-1358795
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-1358803] Downregulation of ERBB2:ERBB3 signaling
(inferredTo)	[Reaction:R-HSA-1358795] Deubiquitination of RNF41 by P-USP8

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