Reactome | Transport of RCbl within the body

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Transport of RCbl within the body Show undefined attributes

created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10100985
displayName	Transport of RCbl within the body
eventOf	[Pathway:R-MMU-196741] Cobalamin (Cbl, vitamin B12) transport and metabolism - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:25562] cobalamin transport
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-MMU-3095901] ABCC1 transports cytosolic RCbl to extracellular region - Mus musculus [Reaction:R-MMU-3000074] TCN2 binds RCbl in the circulation - Mus musculus [Reaction:R-MMU-3000122] CD320 binds extracellular TCN2:RCbl - Mus musculus [BlackBoxEvent:R-MMU-3000112] CD320-mediated TCN2:RCbl uptake and delivery to lysosome - Mus musculus [Reaction:R-MMU-9759206] ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol - Mus musculus [Reaction:R-MMU-9759209] LRP2 binds extracellular TCN2:RCbl - Mus musculus [BlackBoxEvent:R-MMU-9759202] LRP2-mediated TCN2:RCbl uptake and delivery to lysosome - Mus musculus
inferredFrom	[Pathway:R-HSA-9758890] Transport of RCbl within the body - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Transport of RCbl within the body
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48892] Mus musculus
stId	R-MMU-9758890
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-196741] Cobalamin (Cbl, vitamin B12) transport and metabolism
(inferredTo)	[Pathway:R-HSA-9758890] Transport of RCbl within the body

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