Reactome | p-Y342-Ptk6 [cytosol]

authored	[InstanceEdit:9708955] Stephan, Ralf, 2020-12-03
candidateOf	[CandidateSet:R-MMU-8942611] (p-Y342-PTK6,p-Y397-LYN,p-Y226,Y393-ABL1,p-Y419-SRC,p-5Y-JAK2) [cytosol] - Mus musculus
catalystActivities	[CatalystActivity:10075167] protein tyrosine kinase activity of p-Y342-PTK6 [cytosol]
compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-MMU-9709390] p-Y342-Ptk6:p-Y250-Stap2 [cytosol] - Mus musculus [Complex:R-MMU-8848108] p-Y342-PTK6:SOCS3 [cytosol] - Mus musculus
consumedByEvent	[Reaction:R-MMU-8849102] SRMS phosphorylates PTK6 - Mus musculus [Reaction:R-MMU-8849428] PTPN1 binds PTK6 - Mus musculus [Reaction:R-MMU-8848023] Activated PTK6 binds STAP2 - Mus musculus [Reaction:R-MMU-8848751] PTK6 binds AKT1 - Mus musculus [Reaction:R-MMU-8848864] PTK6 binds ARAP1 - Mus musculus [Reaction:R-MMU-8848774] PTK6 binds DOK1 - Mus musculus [Reaction:R-MMU-8848930] PTK6 translocates to the nucleus - Mus musculus [Reaction:R-MMU-8849055] PTK6 binds ARHGAP35 - Mus musculus [Reaction:R-MMU-8848713] PTK6 binds BCAR1 - Mus musculus [Reaction:R-MMU-8848414] Activated PTK6 binds CDKN1B - Mus musculus [Reaction:R-MMU-8848110] SOCS3 binds activated PTK6 - Mus musculus [Reaction:R-MMU-8848596] PTK6 binds PXN - Mus musculus
created	[InstanceEdit:9709348] Stephan, Ralf, 2020-12-14
dbId	9709374
displayName	p-Y342-Ptk6 [cytosol]
endCoordinate	451
hasModifiedResidue	[ModifiedResidue:9709397] O4'-phospho-L-tyrosine at 342
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-8848007] p-Y342-PTK6 [cytosol] - Homo sapiens
maxDepth	1
name	p-Y342-Ptk6 p-Y342-Brk
producedByEvent	[Reaction:R-MMU-8848873] PTK6 phosphorylates ARAP1 - Mus musculus [Reaction:R-MMU-8848776] PTK6 phosphorylates DOK1 - Mus musculus [Reaction:R-MMU-8848726] PTK6 phosphorylates BCAR1 - Mus musculus [Reaction:R-MMU-8848606] PTK6 phosphorylates PXN - Mus musculus [Reaction:R-MMU-8848005] ERBB2 promotes PTK6 autophosphorylation - Mus musculus [Reaction:R-MMU-8849068] PTK6 phosphorylates ARHGAP35 - Mus musculus [Reaction:R-MMU-8848436] PTK6 phosphorylates CDKN1B - Mus musculus
referenceEntity	[ReferenceGeneProduct:uniprot:Q64434] UniProt:Q64434 Ptk6
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48892] Mus musculus
stId	R-MMU-9709374
startCoordinate	1

(hasComponent)	[Complex:R-MMU-9709390] p-Y342-Ptk6:p-Y250-Stap2 [cytosol] [Complex:R-MMU-8849424] p-Y342-PTK6:PTPN1 [cytosol] [Complex:R-MMU-8848108] p-Y342-PTK6:SOCS3 [cytosol] [Complex:R-MMU-8848029] p-Y342-PTK6:STAP2 [cytosol] [Complex:R-MMU-8848073] p-Y342-PTK6:p-Y250-STAP2 [cytosol] [Complex:R-MMU-8848769] p-Y342-PTK6:p-Y315,Y326-AKT1 [cytosol] [Complex:R-MMU-8848750] p-Y342-PTK6:AKT1 [cytosol] [Complex:R-MMU-8848862] p-Y342-PTK6:ARAP1 [cytosol] [Complex:R-MMU-8848773] p-Y342-PTK6:DOK1 [cytosol] [Complex:R-MMU-8849058] p-Y342-PTK6:ARHGAP35 [cytosol] [Complex:R-MMU-8848716] p-Y342-PTK6:BCAR1 [cytosol] [Complex:R-MMU-8848597] p-Y342-PTK6:PXN [cytosol] [Complex:R-MMU-8848415] p-Y342-PTK6:CDKN1B:(CDK4:CCND1,(CDK2:CCNE1)) [cytosol]
(input)	[Reaction:R-MMU-8849102] SRMS phosphorylates PTK6 [Reaction:R-MMU-8849428] PTPN1 binds PTK6 [Reaction:R-MMU-8848110] SOCS3 binds activated PTK6 [Reaction:R-MMU-8848023] Activated PTK6 binds STAP2 [Reaction:R-MMU-8848751] PTK6 binds AKT1 [Reaction:R-MMU-8848864] PTK6 binds ARAP1 [Reaction:R-MMU-8848774] PTK6 binds DOK1 [Reaction:R-MMU-8848930] PTK6 translocates to the nucleus [Reaction:R-MMU-8849055] PTK6 binds ARHGAP35 [Reaction:R-MMU-8848713] PTK6 binds BCAR1 [Reaction:R-MMU-8848596] PTK6 binds PXN [Reaction:R-MMU-8848414] Activated PTK6 binds CDKN1B
(activeUnit)	[CatalystActivity:10074845] protein tyrosine kinase activity of p-Y342-PTK6:STAP2 [cytosol] [CatalystActivity:10074856] protein tyrosine kinase activity of p-Y342-PTK6:p-Y250-STAP2:STAT3 [cytosol] [CatalystActivity:10075187] protein tyrosine kinase activity of p-Y342-PTK6:ARAP1 [cytosol] [CatalystActivity:10075148] protein tyrosine kinase activity of p-Y342-PTK6:AKT1 [cytosol] [CatalystActivity:10075162] protein tyrosine kinase activity of p-Y342-PTK6:DOK1 [cytosol] [CatalystActivity:10075135] protein tyrosine kinase activity of p-Y342-PTK6:BCAR1 [cytosol] [CatalystActivity:10075240] protein tyrosine kinase activity of p-Y342-PTK6:ARHGAP35 [cytosol] [CatalystActivity:10075022] protein tyrosine kinase activity of p-Y342-PTK6:PXN [cytosol] [CatalystActivity:10074990] protein tyrosine kinase activity of p-Y342-PTK6:CDKN1B:(CDK4:CCND1,(CDK2:CCNE1)) [cytosol]
(output)	[Reaction:R-MMU-8848873] PTK6 phosphorylates ARAP1 [Reaction:R-MMU-8848776] PTK6 phosphorylates DOK1 [Reaction:R-MMU-8848726] PTK6 phosphorylates BCAR1 [Reaction:R-MMU-8849068] PTK6 phosphorylates ARHGAP35 [Reaction:R-MMU-8848606] PTK6 phosphorylates PXN [Reaction:R-MMU-8848436] PTK6 phosphorylates CDKN1B [Reaction:R-MMU-8848005] ERBB2 promotes PTK6 autophosphorylation
(physicalEntity)	[CatalystActivity:10075167] protein tyrosine kinase activity of p-Y342-PTK6 [cytosol]
(hasCandidate)	[CandidateSet:R-MMU-8942611] (p-Y342-PTK6,p-Y397-LYN,p-Y226,Y393-ABL1,p-Y419-SRC,p-5Y-JAK2) [cytosol]
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-8848007] p-Y342-PTK6 [cytosol]

p-Y342-Ptk6 [cytosol] Show undefined attributes

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