Reactome | High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane]

Schema > DefinedSet > Entries

compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10020138
displayName	High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane]
hasMember	[Complex:R-MMU-912540] IL3:IL3R active complex, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] - Mus musculus [Complex:R-MMU-926770] High affinity GM-CSF receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] - Mus musculus [Complex:R-MMU-926769] High affinity IL-5 receptor complex dimer, inactive JAK2, phosphorylated Bc:p(Y427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] - Mus musculus
inDisease	false
inferredFrom	[DefinedSet:R-HSA-926768] High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] - Homo sapiens
maxDepth	8
memberOf	[DefinedSet:R-MMU-912533] Interleukin receptor complexes with activated Shc:GRB2:p-GAB2 [plasma membrane] - Mus musculus
name	High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2
schemaClass	DefinedSet
species	[Species:48892] Mus musculus
stId	R-MMU-926768

(hasMember)	[DefinedSet:R-MMU-912533] Interleukin receptor complexes with activated Shc:GRB2:p-GAB2 [plasma membrane]
(inferredTo)	[DefinedSet:R-HSA-926768] High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane]

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