Reactome | Interleukin receptor complexes with activated Shc:GRB2:p-GAB2 [plasma membrane]

Schema > DefinedSet > Entries

compartment	[Compartment:876] plasma membrane
consumedByEvent	[Reaction:R-MMU-508247] Gab2 binds the p85 subunit of Class 1A PI3 kinases - Mus musculus
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10020140
displayName	Interleukin receptor complexes with activated Shc:GRB2:p-GAB2 [plasma membrane]
hasMember	[Complex:R-MMU-912523] IL2:IL2R trimer p(Y338,392,510) beta subunit:p-SHC:GRB2:p(Y)-GAB2 [plasma membrane] - Mus musculus [DefinedSet:R-MMU-926768] High affinity binding complex dimers of cytokine receptors using Bc, inactive JAK2, p(Y593,628)- Bc:p(427,349,350)-SHC1:GRB2:p(Y)-GAB2 [plasma membrane] - Mus musculus
inDisease	false
inferredFrom	[DefinedSet:R-HSA-912533] Interleukin receptor complexes with activated Shc:GRB2:p-GAB2 [plasma membrane] - Homo sapiens
maxDepth	9
name	Interleukin receptor complexes with activated Shc:GRB2:p-GAB2
producedByEvent	[BlackBoxEvent:R-MMU-912527] SHC1 mediates cytokine-induced phosphorylation of GAB2 - Mus musculus
schemaClass	DefinedSet
species	[Species:48892] Mus musculus
stId	R-MMU-912533

(input)	[Reaction:R-MMU-508247] Gab2 binds the p85 subunit of Class 1A PI3 kinases
(output)	[BlackBoxEvent:R-MMU-912527] SHC1 mediates cytokine-induced phosphorylation of GAB2
(inferredTo)	[DefinedSet:R-HSA-912533] Interleukin receptor complexes with activated Shc:GRB2:p-GAB2 [plasma membrane]

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