Reactome | Il15:Il15ra:p-Y-Il2rb:p-Y-Jak1:p-Y-Il2rg:p-Y-Jak3:p-Y-Shc1 binds Grb2

Schema > BlackBoxEvent > Entries

Il15:Il15ra:p-Y-Il2rb:p-Y-Jak1:p-Y-Il2rg:p-Y-Jak3:p-Y-Shc1 binds Grb2 Show undefined attributes

authored	[InstanceEdit:9014998] Duenas, Corina, 2017-08-07
category	omitted
compartment	[Compartment:70101] cytosol [Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:8983354] Duenas, Corina, 2017-03-23
dbId	8983356
displayName	Il15:Il15ra:p-Y-Il2rb:p-Y-Jak1:p-Y-Il2rg:p-Y-Jak3:p-Y-Shc1 binds Grb2
edited	[InstanceEdit:9014998] Duenas, Corina, 2017-08-07
followingEvent	[BlackBoxEvent:R-MMU-9007126] Il15:Il15ra:p-Y-Il2rb:p-Y-Jak1:p-Y-Il2rg:p-Y-Jak3:p-Y-Shc1:Grb2 binds Gab2 - Mus musculus
input	[EntityWithAccessionedSequence:R-MMU-443287] Grb2 [cytosol] [Complex:R-MMU-8983186] Il15:Il15ra:p-Y-Il2rb:p-Y-Il2rg:p-Y-Jak1:p-Y-Jak3:p-Y-Shc [plasma membrane]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:1169463] Shc contains two Grb2 binding sites needed for efficient formation of complexes with SOS in B lymphocytes
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Il15:Il15ra:p-Y-Il2rb:p-Y-Jak1:p-Y-Il2rg:p-Y-Jak3:p-Y-Shc1 binds Grb2 Grb2 binds to the Il15ra:Il15:Il2rb:Jak1:Il2rg:p-Jak3:p-Y-Shc1 complex
orthologousEvent	[Reaction:R-HSA-8983394] IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3:p-Y-SHC1 binds GRB2 - Homo sapiens
output	[Complex:R-MMU-8983178] Il15:Il15ra:p-Y-Il2rb:p-Y-Il2rg:p-Y-Jak1:p-Y-Jak3:p-Y-Shc:Grb2 [plasma membrane]
precedingEvent	[BlackBoxEvent:R-MMU-8983294] Il15ra:Il15:p-Y-Il2rb:p-Y-Jak1:p-Y-Il2rg:p-Y-Jak3 phosphorylates Shc1 - Mus musculus
releaseDate	2017-09-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9014997] Patidar, Manoj, 2017-08-07
schemaClass	BlackBoxEvent
species	[Species:48892] Mus musculus
stId	R-MMU-8983356
summation	[Summation:8983364] GRB2 is recruited by phosphorylated SHC1 in the IL15 recepto...
updateTrackers	[UpdateTracker:9780214] Update Tracker - [BlackBoxEvent:8983356] Il15:Il15ra:p-Y-Il2rb:p-Y-Jak1:p-Y-Il2rg:p-Y-Jak3:p-Y-Shc1 binds Grb2 - v63:[modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9780214] Update Tracker - [BlackBoxEvent:8983356] Il15:Il15ra:p-Y-Il2rb:p-Y-Jak1:p-Y-Il2rg:p-Y-Jak3:p-Y-Shc1 binds Grb2 - v63:[modifyText]
(precedingEvent)	[BlackBoxEvent:R-MMU-9007126] Il15:Il15ra:p-Y-Il2rb:p-Y-Jak1:p-Y-Il2rg:p-Y-Jak3:p-Y-Shc1:Grb2 binds Gab2

Cite Us!