Reactome | Il15ra:Il15:p-Y-Il2rb:p-Y-Jak1:p-Y-Il2rg:p-Y-Jak3 phosphorylates Shc1

Schema > BlackBoxEvent > Entries

Il15ra:Il15:p-Y-Il2rb:p-Y-Jak1:p-Y-Il2rg:p-Y-Jak3 phosphorylates Shc1 Show undefined attributes

authored	[InstanceEdit:9014998] Duenas, Corina, 2017-08-07
category	omitted
compartment	[Compartment:70101] cytosol [Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:8983295] Duenas, Corina, 2017-03-23
dbId	8983294
displayName	Il15ra:Il15:p-Y-Il2rb:p-Y-Jak1:p-Y-Il2rg:p-Y-Jak3 phosphorylates Shc1
edited	[InstanceEdit:9015192] Duenas, Corina, 2017-08-09
followingEvent	[BlackBoxEvent:R-MMU-8983356] Il15:Il15ra:p-Y-Il2rb:p-Y-Jak1:p-Y-Il2rg:p-Y-Jak3:p-Y-Shc1 binds Grb2 - Mus musculus
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [Complex:R-MMU-8983169] Il15:Il15ra:p-Y-Il2rb:p-Y-Il2rg:p-Y-Jak1:p-Y-Jak3:Shc1 [plasma membrane]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:8983265] The docking molecule gab2 is induced by lymphocyte activation and is involved in signaling by interleukin-2 and interleukin-15 but not other common gamma chain-using cytokines [LiteratureReference:507926] New role for Shc in activation of the phosphatidylinositol 3-kinase/Akt pathway
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Il15ra:Il15:p-Y-Il2rb:p-Y-Jak1:p-Y-Il2rg:p-Y-Jak3 phosphorylates Shc1 Shc1 is phosphorylated by Il15ra:Il15:Il2rb:Jak1:Il2rg:p-Jak3:Shc1
orthologousEvent	[BlackBoxEvent:R-HSA-8983309] IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 phosphorylates SHC1 - Homo sapiens
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [Complex:R-MMU-8983186] Il15:Il15ra:p-Y-Il2rb:p-Y-Il2rg:p-Y-Jak1:p-Y-Jak3:p-Y-Shc [plasma membrane]
precedingEvent	[BlackBoxEvent:R-MMU-8983313] Il15:Il15ra:p-Y-Il2rb:p-Y-Jak1:p-Y-Il2rg:p-Y-Jak3 binds Shc1 - Mus musculus
releaseDate	2017-09-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9014997] Patidar, Manoj, 2017-08-07
schemaClass	BlackBoxEvent
species	[Species:48892] Mus musculus
stId	R-MMU-8983294
summation	[Summation:8983305] Interleukin-15 (Il15) stimulates the phosphorylation of Shc...

Referrals

(precedingEvent)

[BlackBoxEvent:R-MMU-8983356] Il15:Il15ra:p-Y-Il2rb:p-Y-Jak1:p-Y-Il2rg:p-Y-Jak3:p-Y-Shc1 binds Grb2

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