Reactome | IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3:p-Y-SHC1 binds GRB2

Schema > Reaction > Entries

IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3:p-Y-SHC1 binds GRB2 Show undefined attributes

authored	[InstanceEdit:9014992] Duenas, Corina, 2017-08-07
category	binding
compartment	[Compartment:70101] cytosol [Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:8983388] Duenas, Corina, 2017-03-23
dbId	8983394
displayName	IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3:p-Y-SHC1 binds GRB2
edited	[InstanceEdit:9015191] Duenas, Corina, 2017-08-09
eventOf	[Pathway:R-HSA-8983432] Interleukin-15 signaling - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-8983384] IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3:p-Y-SHC1:GRB2 binds SOS1,SOS2 - Homo sapiens [BlackBoxEvent:R-HSA-8983425] IL15:IL15RA:IL2RB:JAK1:IL2RG:p-JAK3:p-Y-SHC1:GRB2 binds GAB2 - Homo sapiens
inferredFrom	[BlackBoxEvent:R-MMU-8983356] Il15:Il15ra:p-Y-Il2rb:p-Y-Jak1:p-Y-Il2rg:p-Y-Jak3:p-Y-Shc1 binds Grb2 - Mus musculus
input	[EntityWithAccessionedSequence:R-HSA-8983328] GRB2 [cytosol] [Complex:R-HSA-8983306] IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3:p-Y-SHC1 [plasma membrane]
isChimeric	false
isInDisease	false
isInferred	true
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3:p-Y-SHC1 binds GRB2
output	[Complex:R-HSA-8983330] IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3:p-Y-SHC1:GRB2 [plasma membrane]
precedingEvent	[BlackBoxEvent:R-HSA-8983309] IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 phosphorylates SHC1 - Homo sapiens
releaseDate	2017-09-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9014997] Patidar, Manoj, 2017-08-07
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-8983394
summation	[Summation:8983290] Inferred from mouse:GRB2 is recruited by phosphorylated SHC1...
updateTrackers	[UpdateTracker:9780368] Update Tracker - [Reaction:8983394] IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3:p-Y-SHC1 binds GRB2 - v63:[modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9780368] Update Tracker - [Reaction:8983394] IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3:p-Y-SHC1 binds GRB2 - v63:[modifyText]
(precedingEvent)	[BlackBoxEvent:R-HSA-8983384] IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3:p-Y-SHC1:GRB2 binds SOS1,SOS2 [BlackBoxEvent:R-HSA-8983425] IL15:IL15RA:IL2RB:JAK1:IL2RG:p-JAK3:p-Y-SHC1:GRB2 binds GAB2
(hasEvent)	[Pathway:R-HSA-8983432] Interleukin-15 signaling
(inferredTo)	[BlackBoxEvent:R-MMU-8983356] Il15:Il15ra:p-Y-Il2rb:p-Y-Jak1:p-Y-Il2rg:p-Y-Jak3:p-Y-Shc1 binds Grb2

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