Reactome | Active G alpha (i)?i1/i2/i3 binds RGS proteins

Schema > Reaction > Entries

Active G alpha (i)?i1/i2/i3 binds RGS proteins Show undefined attributes

category	binding
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10084700
displayName	Active G alpha (i)?i1/i2/i3 binds RGS proteins
eventOf	[Pathway:R-MMU-418594] G alpha (i) signalling events - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-MMU-8982020] G alpha (i)?i1/i2/i3 in G (i):RGS complex is inactivated - Mus musculus
inferredFrom	[Reaction:R-HSA-8982019] Active G alpha (i)?i1/i2/i3 binds RGS proteins - Homo sapiens
input	[Complex:R-MMU-392161] G alpha (i): GTP [plasma membrane] [DefinedSet:R-MMU-8982016] RGS1,3,4,5,6,7,8,9,10,11,12,13,14,16,17,18,19,20,21 [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	Active G alpha (i)?i1/i2/i3 binds RGS proteins
output	[Complex:R-MMU-8982011] G alpha (i):GTP:RGS [plasma membrane]
precedingEvent	[Reaction:R-MMU-749454] The Ligand:GPCR:Gi complex dissociates - Mus musculus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-8982019
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-418594] G alpha (i) signalling events
(precedingEvent)	[Reaction:R-MMU-8982020] G alpha (i)?i1/i2/i3 in G (i):RGS complex is inactivated
(inferredTo)	[Reaction:R-HSA-8982019] Active G alpha (i)?i1/i2/i3 binds RGS proteins

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