Reactome | G alpha (i): GTP [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-MMU-8982011] G alpha (i):GTP:RGS [plasma membrane] - Mus musculus [Complex:R-MMU-396910] G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] - Mus musculus
consumedByEvent	[Reaction:R-MMU-8982019] Active G alpha (i)?i1/i2/i3 binds RGS proteins - Mus musculus
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	9997347
displayName	G alpha (i): GTP [plasma membrane]
hasComponent	[DefinedSet:R-MMU-112270] G alpha (i) [plasma membrane] [SimpleEntity:R-ALL-29438] GTP [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-392161] G alpha (i): GTP [plasma membrane] - Homo sapiens
maxDepth	3
name	G alpha (i): GTP
producedByEvent	[Reaction:R-MMU-8964329] G protein alpha (i)-SRC complex dissociates to G protein alpha (i) and Active SRC - Mus musculus [Reaction:R-MMU-749454] The Ligand:GPCR:Gi complex dissociates - Mus musculus [Reaction:R-MMU-392202] Dissociation of the P2Y purinoceptor 12:Gi complex - Mus musculus
schemaClass	Complex
species	[Species:48892] Mus musculus
stId	R-MMU-392161
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-MMU-8982019] Active G alpha (i)?i1/i2/i3 binds RGS proteins
(hasComponent)	[Complex:R-MMU-8982011] G alpha (i):GTP:RGS [plasma membrane] [Complex:R-MMU-8964344] G alpha (i):GTP:SRC-1 [plasma membrane] [Complex:R-MMU-8964231] G protein alpha (i):GTP:p-Y419-SRC [plasma membrane] [Complex:R-MMU-396910] G-protein alpha (i):GTP:Adenylate cyclase [plasma membrane] [Complex:R-MMU-392168] Heterotrimeric G-protein Gi (active) [plasma membrane]
(output)	[Reaction:R-MMU-8964329] G protein alpha (i)-SRC complex dissociates to G protein alpha (i) and Active SRC [Reaction:R-MMU-392202] Dissociation of the P2Y purinoceptor 12:Gi complex [Reaction:R-MMU-749454] The Ligand:GPCR:Gi complex dissociates
(activeUnit)	[CatalystActivity:10084318] protein tyrosine kinase activity of G alpha (i):GTP:SRC-1 [plasma membrane]
(inferredTo)	[Complex:R-HSA-392161] G alpha (i): GTP [plasma membrane]

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