Reactome | SLC25A18,22 import L-Glu, H+

Schema > Reaction > Entries

SLC25A18,22 import L-Glu, H+ Show undefined attributes

catalystActivity	[CatalystActivity:10079688] amino acid:proton symporter activity of SLC25A18,A22 [mitochondrial inner membrane]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:70616] mitochondrial inner membrane [Compartment:5460] mitochondrial matrix
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10079690
displayName	SLC25A18,22 import L-Glu, H+
eventOf	[Pathway:R-MMU-9856872] Malate-aspartate shuttle - Mus musculus [Pathway:R-MMU-442660] SLC-mediated transport of neurotransmitters - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-MMU-70613] GOT2 transaminates OA and L-Glu - Mus musculus
inferredFrom	[Reaction:R-HSA-8875623] SLC25A18,22 import L-Glu, H+ - Homo sapiens
input	[SimpleEntity:R-ALL-70106] H+ [cytosol] [SimpleEntity:R-ALL-29404] L-Glu [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	SLC25A18,22 import L-Glu, H+ SLC25A18,A22 cotransport Glu, H+ from cytosol to mitochondrial matrix
output	[SimpleEntity:R-ALL-113529] H+ [mitochondrial matrix] [SimpleEntity:R-ALL-113552] L-Glu [mitochondrial matrix]
precedingEvent	[Reaction:R-MMU-70592] PXLP-K259-GOT1 transaminates 2-OG and L-Asp - Mus musculus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-8875623
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-442660] SLC-mediated transport of neurotransmitters [Pathway:R-MMU-9856872] Malate-aspartate shuttle
(precedingEvent)	[Reaction:R-MMU-70613] GOT2 transaminates OA and L-Glu
(inferredTo)	[Reaction:R-HSA-8875623] SLC25A18,22 import L-Glu, H+

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