Reactome | EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane]

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EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] Show undefined attributes

compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10078019
displayName	EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane]
hasComponent	[Complex:R-MMU-8875480] CIN85:endophilin [cytosol] [Complex:R-MMU-177505] Clathrin:AP-2 complex [plasma membrane] 2 × [DefinedSet:R-MMU-9624194] EGF-like ligands [extracellular region] [EntityWithAccessionedSequence:R-MMU-182952] EPN1 [plasma membrane] [EntityWithAccessionedSequence:R-MMU-182937] EPS15L1 [plasma membrane] 2 × [EntityWithAccessionedSequence:R-MMU-74686] Grb2 [cytosol] [Complex:R-MMU-8867032] p-Eps15:HGS:STAM [cytosol] 2 × [EntityWithAccessionedSequence:R-MMU-179803] phospho-p-6Y-EGFR [plasma membrane] 2 × [EntityWithAccessionedSequence:R-MMU-182923] phospho-p-Y371-CBL [plasma membrane]
inDisease	false
inferredFrom	[Complex:R-HSA-8867037] EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] - Homo sapiens
maxDepth	5
memberOf	[DefinedSet:R-MMU-8866252] ubiquitinated cargo [plasma membrane] - Mus musculus
name	EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin
schemaClass	Complex
species	[Species:48892] Mus musculus
stId	R-MMU-8867037
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Referrals

(hasMember)	[DefinedSet:R-MMU-8866252] ubiquitinated cargo [plasma membrane]
(inferredTo)	[Complex:R-HSA-8867037] EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane]

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