Reactome | EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane]

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EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] Show undefined attributes

compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:8867038] Rothfels, Karen, 2016-04-05
dbId	8867037
displayName	EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane]
hasComponent	[Complex:R-HSA-8875480] CIN85:endophilin [cytosol] [Complex:R-HSA-177505] Clathrin:AP-2 complex [plasma membrane] 2 × [DefinedSet:R-HSA-9624194] EGF-like ligands [extracellular region] [EntityWithAccessionedSequence:R-HSA-182952] EPN1 [plasma membrane] [EntityWithAccessionedSequence:R-HSA-182937] EPS15L1 [plasma membrane] 2 × [EntityWithAccessionedSequence:R-HSA-74686] GRB2-1 [cytosol] 2 × [EntityWithAccessionedSequence:R-HSA-179803] p-6Y-EGFR [plasma membrane] [Complex:R-HSA-8867032] p-Eps15:HGS:STAM [cytosol] 2 × [EntityWithAccessionedSequence:R-HSA-182923] p-Y371-CBL [plasma membrane]
inDisease	false
includedLocation	[Compartment:70101] cytosol [Compartment:984] extracellular region
inferredTo	[Complex:R-MMU-8867037] EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] - Mus musculus [Complex:R-RNO-8867037] EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] - Rattus norvegicus [Complex:R-CFA-8867037] EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] - Canis familiaris [Complex:R-BTA-8867037] EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] - Bos taurus [Complex:R-SSC-8867037] EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] - Sus scrofa [Complex:R-XTR-8867037] EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] - Xenopus tropicalis [Complex:R-GGA-8867037] EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] - Gallus gallus [Complex:R-DME-8867037] EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] - Drosophila melanogaster [Complex:R-CEL-8867037] EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] - Caenorhabditis elegans
maxDepth	5
memberOf	[DefinedSet:R-HSA-8866252] ubiquitinated cargo [plasma membrane] - Homo sapiens
modified	[InstanceEdit:9824819] Orlic-Milacic, Marija, 2023-01-22
name	EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin EGF:Phospho-EGFR (Y1045) dimer:Phospho-CBL:GRB2:CIN85:Endophilin:Epsin:Eps15R:Eps15 complex:Clathrin EGF:Phospho-EGFR (Y1069) dimer:Phospho-CBL:GRB2:CIN85:Endophilin:Epsin:Eps15R:Eps15 complex:Clathrin
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-8867037
updateTrackers	[UpdateTracker:9896394] Update Tracker - [Complex:8867037] EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] - v60:[updateContainedComponent] [UpdateTracker:9905067] Update Tracker - [Complex:8867037] EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] - v84:[addName] [UpdateTracker:9899851] Update Tracker - [Complex:8867037] EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [plasma membrane] - v67:[add_removeHasComponent, modifyName]

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[DefinedSet:R-HSA-8866252] ubiquitinated cargo [plasma membrane]

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