Reactome | HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1 [plasma membrane]

Schema > DefinedSet > Entries

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-MMU-8865998] HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:PTPN11 [plasma membrane] - Mus musculus
consumedByEvent	[Reaction:R-MMU-8865994] GAB1 binds PTPN11 - Mus musculus [Reaction:R-MMU-8851954] Phosphorylated GAB1 recruits PI3K to MET - Mus musculus [Reaction:R-MMU-8875540] GAB1 recruits CRK,CRKL to MET - Mus musculus
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10044176
displayName	HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1 [plasma membrane]
hasMember	[Complex:R-MMU-8851942] HGF:p-4Y-MET dimer:GRB2-1:p-5Y-GAB1 [plasma membrane] - Mus musculus [Complex:R-MMU-8851941] HGF:p-4Y-MET dimer:p-5Y-GAB1 [plasma membrane] - Mus musculus
inDisease	false
inferredFrom	[DefinedSet:R-HSA-8851943] HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1 [plasma membrane] - Homo sapiens
maxDepth	6
name	HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1
producedByEvent	[Reaction:R-MMU-8851933] MET phosphorylates GAB1 - Mus musculus
schemaClass	DefinedSet
species	[Species:48892] Mus musculus
stId	R-MMU-8851943

(input)	[Reaction:R-MMU-8865994] GAB1 binds PTPN11 [Reaction:R-MMU-8851954] Phosphorylated GAB1 recruits PI3K to MET [Reaction:R-MMU-8875540] GAB1 recruits CRK,CRKL to MET
(hasComponent)	[Complex:R-MMU-8865998] HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:PTPN11 [plasma membrane] [Complex:R-MMU-8875548] HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:CRK,CRKL [plasma membrane] [Complex:R-MMU-8851953] HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1:PI3K [plasma membrane]
(output)	[Reaction:R-MMU-8851933] MET phosphorylates GAB1
(inferredTo)	[DefinedSet:R-HSA-8851943] HGF:p-4Y-MET:p-5Y-GAB1, HGF:p-4Y-MET:GRB2-1:p-5Y-GAB1 [plasma membrane]

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