Reactome | Signaling by PTK6

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Signaling by PTK6 Show undefined attributes

created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10101437
displayName	Signaling by PTK6
eventOf	[Pathway:R-MMU-9006927] Signaling by Non-Receptor Tyrosine Kinases - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	true
hasEHLD	false
hasEvent	[Pathway:R-MMU-8847993] ERBB2 Activates PTK6 Signaling - Mus musculus [Pathway:R-MMU-8849474] PTK6 Activates STAT3 - Mus musculus [Pathway:R-MMU-8849470] PTK6 Regulates Cell Cycle - Mus musculus [Pathway:R-MMU-8849471] PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases - Mus musculus [Pathway:R-MMU-8849468] PTK6 Regulates Proteins Involved in RNA Processing - Mus musculus [Pathway:R-MMU-8849469] PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 - Mus musculus [Pathway:R-MMU-8857538] PTK6 promotes HIF1A stabilization - Mus musculus [Pathway:R-MMU-8849472] PTK6 Down-Regulation - Mus musculus
inferredFrom	[Pathway:R-HSA-8848021] Signaling by PTK6 - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	3
name	Signaling by PTK6
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48892] Mus musculus
stId	R-MMU-8848021
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-9006927] Signaling by Non-Receptor Tyrosine Kinases
(hasEncapsulatedEvent)	[Pathway:R-MMU-453279] Mitotic G1 phase and G1/S transition [Pathway:R-MMU-1227986] Signaling by ERBB2
(inferredTo)	[Pathway:R-HSA-8848021] Signaling by PTK6

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