Reactome | ERBB2 Activates PTK6 Signaling

Schema > Pathway > Entries

created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10101435
displayName	ERBB2 Activates PTK6 Signaling
eventOf	[Pathway:R-MMU-8848021] Signaling by PTK6 - Mus musculus [Pathway:R-MMU-1227986] Signaling by ERBB2 - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-MMU-8847995] Activated ERBB2 binds PTK6 (BRK) - Mus musculus [Reaction:R-MMU-8848005] ERBB2 promotes PTK6 autophosphorylation - Mus musculus
inferredFrom	[Pathway:R-HSA-8847993] ERBB2 Activates PTK6 Signaling - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	ERBB2 Activates PTK6 Signaling
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48892] Mus musculus
stId	R-MMU-8847993
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-MMU-1227986] Signaling by ERBB2 [Pathway:R-MMU-8848021] Signaling by PTK6
(inferredTo)	[Pathway:R-HSA-8847993] ERBB2 Activates PTK6 Signaling

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