Reactome | Interconversion of 2-oxoglutarate and 2-hydroxyglutarate

Schema > Pathway > Entries

Interconversion of 2-oxoglutarate and 2-hydroxyglutarate Show undefined attributes

created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10100479
displayName	Interconversion of 2-oxoglutarate and 2-hydroxyglutarate
eventOf	[Pathway:R-MMU-1428517] Aerobic respiration and respiratory electron transport - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:10930] 2-oxoglutarate metabolic process
hasDiagram	true
hasEHLD	false
hasEvent	[Reaction:R-MMU-880050] (S)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 - Mus musculus [Reaction:R-MMU-880007] (R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 - Mus musculus [Reaction:R-MMU-880002] (R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate - Mus musculus [Reaction:R-MMU-880033] 2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde - Mus musculus
inferredFrom	[Pathway:R-HSA-880009] Interconversion of 2-oxoglutarate and 2-hydroxyglutarate - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Interconversion of 2-oxoglutarate and 2-hydroxyglutarate
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48892] Mus musculus
stId	R-MMU-880009
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEncapsulatedEvent)	[Pathway:R-MMU-71403] Citric acid cycle (TCA cycle)
(inferredTo)	[Pathway:R-HSA-880009] Interconversion of 2-oxoglutarate and 2-hydroxyglutarate
(hasEvent)	[Pathway:R-MMU-1428517] Aerobic respiration and respiratory electron transport

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