Reactome | USP9X [cytosol]

Schema > EntityWithAccessionedSequence > Entries

candidateOf	[CandidateSet:R-MMU-9019558] RHOU effectors [cytosol] - Mus musculus [CandidateSet:R-MMU-9020366] RHOV effectors [cytosol] - Mus musculus
compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-MMU-870520] Ub-SMAD4:USP9X [cytosol] - Mus musculus [Complex:R-MMU-9033512] USP9X:Ub:PEX5L [cytosol] - Mus musculus
consumedByEvent	[Reaction:R-MMU-870479] USP9X (FAM) binds to ubiquitinated SMAD4 - Mus musculus [Reaction:R-MMU-9033509] USP9X binds Ub:PEX5L - Mus musculus
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10020833
displayName	USP9X [cytosol]
endCoordinate	2554
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-870499] USP9X [cytosol] - Homo sapiens
maxDepth	1
memberOf	[DefinedSet:R-MMU-8853523] UCHL3,USP7,USP9X [cytosol] - Mus musculus
name	USP9X P70398
producedByEvent	[Reaction:R-MMU-9033491] USP9X hydrolyzes Ub:PEX5L yielding PEX5L and Ubiquitin - Mus musculus [Reaction:R-MMU-870437] USP9X (FAM) deubiquitinates SMAD4 - Mus musculus
referenceEntity	[ReferenceGeneProduct:uniprot:P70398] UniProt:P70398
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48892] Mus musculus
stId	R-MMU-870499
startCoordinate	1

(hasCandidate)	[CandidateSet:R-MMU-9020366] RHOV effectors [cytosol] [CandidateSet:R-MMU-9019558] RHOU effectors [cytosol]
(output)	[Reaction:R-MMU-9033491] USP9X hydrolyzes Ub:PEX5L yielding PEX5L and Ubiquitin [Reaction:R-MMU-870437] USP9X (FAM) deubiquitinates SMAD4
(activeUnit)	[CatalystActivity:10087320] cysteine-type deubiquitinase activity of USP9X:Ub:PEX5L [cytosol] [CatalystActivity:10020839] cysteine-type deubiquitinase activity of Ub-SMAD4:USP9X [cytosol]
(input)	[Reaction:R-MMU-9033509] USP9X binds Ub:PEX5L [Reaction:R-MMU-870479] USP9X (FAM) binds to ubiquitinated SMAD4
(hasComponent)	[Complex:R-MMU-9033512] USP9X:Ub:PEX5L [cytosol] [Complex:R-MMU-870520] Ub-SMAD4:USP9X [cytosol]
(hasMember)	[DefinedSet:R-MMU-8853523] UCHL3,USP7,USP9X [cytosol]
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-870499] USP9X [cytosol]

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