Reactome | USP9X [cytosol]

candidateOf	[CandidateSet:R-HSA-9019558] RHOU effectors [cytosol] - Homo sapiens [CandidateSet:R-HSA-9020366] RHOV effectors [cytosol] - Homo sapiens
compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-5661162] USPX9:SNCA [cytosol] - Homo sapiens [Complex:R-HSA-9033494] USP9X:Ub:PEX5S [cytosol] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-9033526] USP9X binds Ub:PEX5S - Homo sapiens [Reaction:R-HSA-5661157] USP9X binds Ub-SNCA - Homo sapiens [Reaction:R-HSA-870479] USP9X (FAM) binds to ubiquitinated SMAD4 - Homo sapiens [Reaction:R-HSA-9033509] USP9X binds Ub:PEX5L - Homo sapiens
created	[InstanceEdit:870527] Williams, MG, 2010-06-08
dbId	870499
displayName	USP9X [cytosol]
endCoordinate	2554
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-870499] USP9X [cytosol] - Mus musculus [EntityWithAccessionedSequence:R-RNO-870499] Usp9x [cytosol] - Rattus norvegicus [EntityWithAccessionedSequence:R-BTA-870499] USP9X [cytosol] - Bos taurus [EntityWithAccessionedSequence:R-SSC-870499] USP9X [cytosol] - Sus scrofa [EntityWithAccessionedSequence:R-XTR-870499] usp9x [cytosol] - Xenopus tropicalis [EntityWithAccessionedSequence:R-GGA-870499] USP9 [cytosol] - Gallus gallus [EntityWithAccessionedSequence:R-DME-870499] faf [cytosol] - Drosophila melanogaster
maxDepth	1
memberOf	[DefinedSet:R-HSA-8853523] UCHL3,USP7,USP9X [cytosol] - Homo sapiens
modified	[InstanceEdit:9851828] D'Eustachio, Peter, 2023-10-31
name	USP9X FAM Probable ubiquitin carboxyl-terminal hydrolase FAF-X
producedByEvent	[Reaction:R-HSA-5661161] USP9X:SNCA dissociates - Homo sapiens [Reaction:R-HSA-9033491] USP9X hydrolyzes Ub:PEX5L yielding PEX5L and Ubiquitin - Homo sapiens [Reaction:R-HSA-870437] USP9X (FAM) deubiquitinates SMAD4 - Homo sapiens [Reaction:R-HSA-9033478] USP9X hydrolyzes Ub:PEX5S yielding PEX5S and Ubiquitin - Homo sapiens
referenceEntity	[ReferenceGeneProduct:uniprot:Q93008] UniProt:Q93008 USP9X
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-870499
startCoordinate	1
updateTrackers	[UpdateTracker:9906556] Update Tracker - [EntityWithAccessionedSequence:870499] USP9X [cytosol] - v87:[modifyEndCoordinate]

(updatedInstance)	[UpdateTracker:9906556] Update Tracker - [EntityWithAccessionedSequence:870499] USP9X [cytosol] - v87:[modifyEndCoordinate]
(hasCandidate)	[CandidateSet:R-HSA-9020366] RHOV effectors [cytosol] [CandidateSet:R-HSA-9019558] RHOU effectors [cytosol]
(input)	[Reaction:R-HSA-9033526] USP9X binds Ub:PEX5S [Reaction:R-HSA-9033509] USP9X binds Ub:PEX5L [Reaction:R-HSA-5661157] USP9X binds Ub-SNCA [Reaction:R-HSA-870479] USP9X (FAM) binds to ubiquitinated SMAD4
(output)	[Reaction:R-HSA-9033491] USP9X hydrolyzes Ub:PEX5L yielding PEX5L and Ubiquitin [Reaction:R-HSA-9033478] USP9X hydrolyzes Ub:PEX5S yielding PEX5S and Ubiquitin [Reaction:R-HSA-5661161] USP9X:SNCA dissociates [Reaction:R-HSA-870437] USP9X (FAM) deubiquitinates SMAD4
(activeUnit)	[CatalystActivity:9033483] cysteine-type deubiquitinase activity of USP9X:Ub:PEX5L [cytosol] [CatalystActivity:9033480] cysteine-type deubiquitinase activity of USP9X:Ub:PEX5S [cytosol] [CatalystActivity:5661160] cysteine-type peptidase activity of USP9X:Ub-SNCA [cytosol] [CatalystActivity:870516] cysteine-type deubiquitinase activity of Ub-SMAD4:USP9X [cytosol]
(hasComponent)	[Complex:R-HSA-9033494] USP9X:Ub:PEX5S [cytosol] [Complex:R-HSA-9033512] USP9X:Ub:PEX5L [cytosol] [Complex:R-HSA-5661162] USPX9:SNCA [cytosol] [Complex:R-HSA-5661158] USP9X:Ub-SNCA [cytosol] [Complex:R-HSA-870520] Ub-SMAD4:USP9X [cytosol]
(hasMember)	[DefinedSet:R-HSA-8853523] UCHL3,USP7,USP9X [cytosol]

USP9X [cytosol] Show undefined attributes

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