Reactome | FASL binds FAS Receptor

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FASL binds FAS Receptor Show undefined attributes

category	binding
compartment	[Compartment:876] plasma membrane [Compartment:984] extracellular region
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	9989969
displayName	FASL binds FAS Receptor
eventOf	[Pathway:R-MMU-75157] FasL/ CD95L signaling - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-MMU-71050] Trimerization of the FASL:FAS receptor complex - Mus musculus
goBiologicalProcess	[GO_BiologicalProcess:2133497] apoptotic signaling pathway
inferredFrom	[Reaction:R-HSA-75244] FASL binds FAS Receptor - Homo sapiens
input	[EntityWithAccessionedSequence:R-MMU-66248] Fas [plasma membrane] [EntityWithAccessionedSequence:R-MMU-66212] Faslg [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	FASL binds FAS Receptor
output	[Complex:R-MMU-76564] FASL:FAS Receptor monomer [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-75244
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-75157] FasL/ CD95L signaling
(precedingEvent)	[Reaction:R-MMU-71050] Trimerization of the FASL:FAS receptor complex
(inferredTo)	[Reaction:R-HSA-75244] FASL binds FAS Receptor

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