Reactome | Trimerization of the FASL:FAS receptor complex

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Trimerization of the FASL:FAS receptor complex Show undefined attributes

category	binding
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	9986894
displayName	Trimerization of the FASL:FAS receptor complex
eventOf	[Pathway:R-MMU-75157] FasL/ CD95L signaling - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-MMU-83650] FasL:Fas binds FADD - Mus musculus
inferredFrom	[Reaction:R-HSA-71050] Trimerization of the FASL:FAS receptor complex - Homo sapiens
input	3 × [Complex:R-MMU-76564] FASL:FAS Receptor monomer [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	Trimerization of the FASL:FAS receptor complex
output	[Complex:R-MMU-76195] FASL:FAS Receptor Trimer [plasma membrane]
precedingEvent	[Reaction:R-MMU-75244] FASL binds FAS Receptor - Mus musculus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-71050
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-75157] FasL/ CD95L signaling
(precedingEvent)	[Reaction:R-MMU-83650] FasL:Fas binds FADD
(inferredTo)	[Reaction:R-HSA-71050] Trimerization of the FASL:FAS receptor complex

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