Reactome | GSTZ1 isomerizes 4-MAA

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GSTZ1 isomerizes 4-MAA Show undefined attributes

catalystActivity	[CatalystActivity:9986961] maleylacetoacetate isomerase activity of GSTZ1 dimer [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	9986963
displayName	GSTZ1 isomerizes 4-MAA
eventOf	[Pathway:R-MMU-8963684] Tyrosine catabolism - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-MMU-71181] FAH cleaves 4FAA - Mus musculus
inferredFrom	[Reaction:R-HSA-71173] GSTZ1 isomerizes 4-MAA - Homo sapiens
input	[SimpleEntity:R-ALL-31135] 4MAA [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	GSTZ1 isomerizes 4-MAA 4-maleylacetoacetate => 4-fumarylacetoacetate maleylacetoacetate => fumarylacetoacetate
output	[SimpleEntity:R-ALL-31175] 4FAA [cytosol]
precedingEvent	[Reaction:R-MMU-71164] HGD dioxygenates homogentisate - Mus musculus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-71173
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-8963684] Tyrosine catabolism
(precedingEvent)	[Reaction:R-MMU-71181] FAH cleaves 4FAA
(inferredTo)	[Reaction:R-HSA-71173] GSTZ1 isomerizes 4-MAA

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