Reactome | Tp53bp1 [nucleoplasm]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-MMU-5693591] DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:TP53BP1 [nucleoplasm] - Mus musculus
consumedByEvent	[Reaction:R-MMU-2997723] PIAS4 SUMOylates TP53BP1 with SUMO1 - Mus musculus [Reaction:R-MMU-5693566] TP53BP1 associates with H4K20Me2 at DNA DSBs - Mus musculus
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10046973
displayName	Tp53bp1 [nucleoplasm]
endCoordinate	1972
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-61175] TP53BP1 [nucleoplasm] - Homo sapiens
maxDepth	1
name	Tp53bp1 TP53BP1 P70399
referenceEntity	[ReferenceGeneProduct:uniprot:P70399] UniProt:P70399
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48892] Mus musculus
stId	R-MMU-61175
startCoordinate	1

(input)	[Reaction:R-MMU-2997723] PIAS4 SUMOylates TP53BP1 with SUMO1 [Reaction:R-MMU-5693566] TP53BP1 associates with H4K20Me2 at DNA DSBs
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-61175] TP53BP1 [nucleoplasm]
(hasComponent)	[Complex:R-MMU-5693591] DNA DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:K63PolyUb-K14,K16,p-S139-H2AFX,Me2K21-HIST1H4A-Nucleosome:p-5T-MDC1:p-S102-WHSC1:RNF8:Zn2+:SUMO1:p-T4827-HERC2:UBE2N:UBE2V2:RNF168:PIAS4:TP53BP1 [nucleoplasm]

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