Reactome | Ttf-I binds the T0 region (Sal Box) of the rDNA

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Ttf-I binds the T0 region (Sal Box) of the rDNA Show undefined attributes

authored	[InstanceEdit:565730] May, B, 2010-04-06
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:573322] May, B, 2010-04-10
dbId	573369
deleted	[Deleted:9032446] Deletion of instance: 573389 [Deleted:9032440] Deletion of instance: 5334727
displayName	Ttf-I binds the T0 region (Sal Box) of the rDNA
edited	[InstanceEdit:565730] May, B, 2010-04-06
followingEvent	[Reaction:R-MMU-573336] Nucleolar Chromatin Remodeling Complex (NoRC) binds intergenic spacer of rRNA gene - Mus musculus
input	[EntityWithAccessionedSequence:R-MMU-5096480] T0 region of rDNA [nucleoplasm] [EntityWithAccessionedSequence:R-MMU-573306] Ttf1 [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:74988] Molecular coevolution of mammalian ribosomal gene terminator sequences and the transcription termination factor TTF-I. [LiteratureReference:5211368] Chromatin-specific regulation of mammalian rDNA transcription by clustered TTF-I binding sites [LiteratureReference:74990] A repeated 18 bp sequence motif in the mouse rDNA spacer mediates binding of a nuclear factor and transcription termination. [LiteratureReference:427458] Epigenetic regulation of TTF-I-mediated promoter-terminator interactions of rRNA genes [LiteratureReference:5219066] The chromatin remodeling complex NoRC and TTF-I cooperate in the regulation of the mammalian rRNA genes in vivo
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Ttf-I binds the T0 region (Sal Box) of the rDNA
orthologousEvent	[Reaction:R-HSA-74987] TTF-I binds to the Sal Box - Homo sapiens
output	[Complex:R-MMU-573309] Ttf-I:T0 region of rDNA [nucleoplasm]
precedingEvent	[BlackBoxEvent:R-MMU-573343] Cleavage of intergenic spacer RNA to yield fragments of 150-300 nucleotides - Mus musculus
releaseDate	2014-03-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:5332991] Shiao, YH, 2014-02-18 [InstanceEdit:8856904] Iben, Sebastian, 2016-02-12
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-573369
summation	[Summation:573327] The Transcription termination factor (Ttf1, also known as Tt...

Referrals

(replacementInstances)	[Deleted:9032440] Deletion of instance: 5334727 [Deleted:9032446] Deletion of instance: 573389
(precedingEvent)	[Reaction:R-MMU-573336] Nucleolar Chromatin Remodeling Complex (NoRC) binds intergenic spacer of rRNA gene

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