Reactome | CX3 complex binds D-loop structures

Schema > Reaction > Entries

CX3 complex binds D-loop structures Show undefined attributes

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10061069
displayName	CX3 complex binds D-loop structures
eventOf	[Pathway:R-MMU-5693579] Homologous DNA Pairing and Strand Exchange - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-MMU-5693593] D-loop extension by DNA polymerases - Mus musculus
inferredFrom	[Reaction:R-HSA-5685838] CX3 complex binds D-loop structures - Homo sapiens
input	[Complex:R-MMU-5685311] CX3 complex [nucleoplasm] [Complex:R-MMU-5685658] D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	CX3 complex binds D-loop structures
output	[Complex:R-MMU-5685826] D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm]
precedingEvent	[Reaction:R-MMU-5685319] CX3 complex formation - Mus musculus [Reaction:R-MMU-5693620] D-loop formation mediated by PALB2, BRCA2 and RAD51 - Mus musculus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-5685838
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-5693579] Homologous DNA Pairing and Strand Exchange
(precedingEvent)	[Reaction:R-MMU-5693593] D-loop extension by DNA polymerases
(inferredTo)	[Reaction:R-HSA-5685838] CX3 complex binds D-loop structures